Bölüm "İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı" WoS İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 68, listelenen: 1-20
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ABCG5 and ABCG8 gene polymorphisms in type 2 diabetes mellitus in the Turkish population
(Elsevier, 2015)Objective: The aim of the present study was to investigate the relationship between ABCG5 and ABCG8 gene polymorphisms and plasma lipid concentrations in Turkish patients with type 2 diabetes mellitus. Methods: Included ... -
Active shrinkage protects neurons following axonal transection
(Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
(Frontiers Media Sa, 2019)Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ... -
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ... -
Cardiac immunology: A new era for immune cells in the heart
(Plenum Press, 2021)The immune system is essential for the development and homeostasis of the human body. Our current understanding of the immune system on disease pathogenesis has drastically expanded over the last decade with the definition ... -
Clopidogrel exerts neuroprotective effect in experimental traumatic brain injury
(Wiley-Blackwell, 2016)... -
Cytokine gene polymorphism frequencies in Turkish population living in Marmara region
(De Gruyter Open Ltd, 2022)Objectives Sequence variants in cytokine genes are related to affect cytokine gene levels. In this study, it was aimed to examine eight single nucleotide polymorphisms (SNPs) in five cytokine genes (TNF-alpha, INF-gamma, ... -
Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
(Elsevier Inc., 2021)Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ... -
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines
(Elsevier Inc., 2022)Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of ... -
Design of IKVAV peptide/gold nanoparticle decorated, micro/nano-channeled PCL/PLGA film scaffolds for neuronal differentiation and neurite outgrowth
(Elsevier Ltd, 2023)In the field of neural tissue engineering, intensive efforts are being made to develop tissue scaffolds that can support an effective functional recovery and neural development by guiding damaged axons and neurites. ... -
DNA repair genes and chronic myeloid leukemia: ERCC2 (751), XRCC1 (399), XRCC4-Intron 3, XRCC4 (-1394) gene polymorphisms
(Mattioli 1885, 2021)To the editor. Chronic myeloid leukemia (CML), which is characterized by the overproduction of mature cells in the granulocytic series, is included in the group of chronic myeloproliferative neoplasms.1 It is the first ... -
Dose-dependent neuroprotective effect of enoxaparin on cold-induced traumatic brain injury
(Medknow Publications & Media Pvt Ltd., 2017)Recent evidence exists that enoxaparin can reduce brain injury because of its anticoagulant activity. To investigate the potential therapeutic effect of enoxaparin on cold-induced traumatic brain injury, at 20 minutes after ... -
Editorial "Stem cells: Biology, genetics, and epigenetics"
(Tubitak Scientific & Technical Research Council Turkey, 2016)Gene therapy, stem cells, and most recently genome editing via CRISPR/CAS9 are among the terms/ methodology that continue to ignite the imagination of all biologists. They hold the potential to overcome previously incurable ... -
The effect of melatonin on the exosome release and content in in vitro amyloid-beta toxicity model
(Wiley-Blackwell, 2016)... -
The effect of systemic rifampicin treatment on inferior alveolar nerve regeneration in rats following crush injury
(Wiley, 2020)Axonal regeneration of the inferior alveolar nerve (IAN) is a therapeutic target for functional recovery after peripheral nerve injury. Rifampicin exerts anti-apoptotic, anti-inflammatory, and anti-oxidant effects on nerve ... -
The effect of ultrasound-guided serratus plane block on the quality of life in patients undergoing modified radical mastectomy and axillary lymph node dissection: A randomized controlled study
(NLM (Medline), 2022)BACKGROUND: Modified radical mastectomy (MRM) and axillary lymph node dissection (AD) are the most commonly used surgical methods in breast cancer surgery, and they are characterized by moderate to severe pain. This study ... -
Effects of foeniculum vulgare essential oil compounds, fenchone and limonene, on experimental wound healing
(Taylor and Francis Ltd, 2017)We investigated the wound healing efficacy of the Foeniculum vulgare compounds, fenchone and limonene, using an excisional cutaneous wound model in rats. An excision wound was made on the back of the rat and fenchone and ... -
Effects of neurotrophic factors cdnf and manf on brain plasticity and repair after brain ischemia
(Wiley-Blackwell, 2016)...