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Gilteritinib (XOSPATA (R)) in Turkey: Early access program results
(Mattioli 1885, 2023)Background And Objectives: Gilteritinib (XOSPATA (R), Astellas) is a type I oral FLT3 inhibitor, a tyrosine kinase AXL inhibitor, involved in both c-Kit and FMS-like tyrosine kinase 3 (FLT3) resistance. In the phase 3 ... -
Gingival crevicular fluid tissue/blood vessel-type plasminogen activator and plasminogen activator inhibitor-2 levels in patients with rheumatoid arthritis: Effects of nonsurgical periodontal therapy
(Wiley, 2017)Background and ObjectiveThe aim of this study was to evaluate the effect of nonsurgical periodontal therapy on clinical parameters and gingival crevicular fluid levels of tissue/blood vessel-type plasminogen activator ... -
A GIPC1-palmitate switch modulates dopamine drd3 receptor trafficking and signaling
(Amer Soc Microbiology, 2016)Palmitoylation is involved in several neuropsychiatric and movement disorders for which a dysfunctional signaling of the dopamine D3 receptor (Drd3) is hypothesized. Computational modeling of Drd3's homologue, Drd2, has ... -
Giving risk management culture a role in strategic planning
(Springer International Publishing Ag, 2017)Strategically planned and implemented risk management paves the way for competitive advantage and a decisive edge for global financial institutions. The importance of risk management becomes more evident in financial ... -
Glacial lakes mapping using multi satellite PlanetScope imagery and deep learning
(MDPI AG, 2020)Glacial lakes mapping using satellite remote sensing data are important for studying the effects of climate change as well as for the mitigation and risk assessment of a Glacial Lake Outburst Flood (GLOF). The 3U cubesat ... -
Glandular odontogenic cyst: Case series
(Medknow Publications & Media Pvt Ltd, 2017)Glandular odontogenic cyst (GOC) is an uncommon and aggressive jaw cyst with a high recurrence rate. It may grow into a large size. Diagnosis of the cyst is challenging since it may be confused with some other jaw cysts ... -
Glass: Global lorlatinib for ALK(+) and ROS1(+) retrospective study: Real world data of 123 NSCLC patients
(Elsevier Science Inc, 2021)Introduction: Lorlatinib is a third-generation tyrosine-kinases inhibitor (TKI) targeting ALK/ROS1 fusions. The FDA has approved lorlatinib for TKI-pretreated ALK(+) NSCLC, while its approval for ROS1(+) is still pending. ... -
Glass: Global lorlatinib for ALK(+) and ROS1(+) retrospective study: Real world data of 123 NSCLC patients
(Elsevier Ireland Ltd, 2020)Lorlatinib is a third-generation tyrosine-kinases inhibitor (TKI) targeting ALK/ROS1 fusions. The FDA has approved lorlatinib for TKI-pretreated ALK(+) NSCLC, while its approval for ROS1( + ) is still pending. Here we ... -
Glaucoma detection using image processing techniques: A literature review
(Elsevier, 2019)The term glaucoma refers to a group of heterogeneous diseases that cause the degeneration of retinal ganglion cells (RGCs). The degeneration of RGCs leads to two main issues: (i) structural changes to the optic nerve head ... -
Global business strategies in crisis strategic thinking and development preface
(Springer International Publishing Ag, 2017)The latest economic turmoil with its reflections on business performance forced top managers to develop effective business strategies in order to boost effiency at company level. The latest global financial crisis also ... -
Global consensus recommendations on menopause in the workplace: A European Menopause and Andropause Society (EMAS) position statement
(Elsevier Ireland Ltd, 2021)Introduction: Worldwide, there are 657 million women aged 45-59 and around half contribute to the labor force during their menopausal years. There is a diversity of experience of menopause in the workplace. It is shaped ... -
Global financial crisis and Its ramifications on capital markets opportunities and threats in volatile economic conditions preface
(Springer International Publishing AG, 2017)The latest global financial crisis and its ramifications on capital markets have led to a growing attention on investment decisions in emerging markets. During the year, doubts related to the debt crisis in the Euro zone ... -
Global research on hereditary hearing impairment over the last 40 years: A bibliometric study
(Aves, 2021)BACKGROUND: Research on hereditary hearing impairment has had several boosts to identify deafness-causing genes. The number of studies regarding the diagnosis and treatment modalities of hereditary hearing impairment is ... -
Global research on maxillofacial fracture over the last 40 years: A bibliometric study
(Lippincott Williams & Wilkins, 2021)Maxillofacial injuries are widely investigated worldwide as it consists a significant portion of trauma patients. Many researchers from various regions have reported the clinical and statistical analyses of maxillofacial ... -
Glofitamab in relapsed/refractory diffuse large B cell lymphoma: Real world data
(American Society of Hematology, 2022)Abstract INTRODUCT ̇ION Glofitamab is a T-cell-engaging bispecific antibody connecting CD20 on B cells and CD3 on T cells. Although, most of the patients with B-cell non-Hodgkin lymphoma (BNHL) achieve complete response ... -
Glofitamab in relapsed/refractory diffuse large B-cell lymphoma: Real-world data
(Wiley, 2023)Glofitamab is a CD3xCD20 bi-specific antibody with two fragments directed to the CD20 antigen and a single CD3-binding fragment. Encouraging response and survival rates were recently reported in a pivotal phase II expansion ... -
Glucocorticoids in a neonatal hyperoxic lung injury model: Pulmonary and neurotoxic effects
(Springer Nature, 2022)Background We aimed to compare the effect of dexamethasone (Dex), hydrocortisone (Hc), and methylprednisolone (Mpz) at equivalent doses on somatic growth, lung healing, and neurotoxicity in a hyperoxic rat model. We ... -
Glucosamine-sulfate on fracture healing
(Turkısh Assoc Trauma Emergency Surgery, 2013)BACKGROUND The aim of this study is to determine whether glucosamine-sulfate has any effects on bone-healing. METHODS A unilateral fracture was created in the tibia of sixty-one female rats. Rats were given no drug or 230 ... -
Gluteoperinealis muscle: A surgically important variation
(Springer France, 2021)Background Anatomical variations are common in gluteal region. This report presents two cases of gluteoperinealis muscles detected during radiological imaging. Case presentation Our study was conducted on two patients. ... -
Glycemic index values of monofloral Turkish honeys and the effect of their consumption on glucose metabolism
(Tubitak Scientific & Technical Research Council Turkey, 2016)Background/aim: Clinical trials have shown that low glycemic index (GI) nutrition reduces mean blood glucose concentrations and insulin secretions. The aim of the present study was to determine the GI values of various ...
