Bölüm "İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Farmakoloji Ana Bilim Dalı" TR-Dizin İndeksli Yayınlar Koleksiyonu için listeleme
Toplam kayıt 41, listelenen: 1-20
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An alternative approach wound healing field with polypodium vulgare
(Logos Medical Publishing, 2020)Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ... -
Arctium minus metanol ekstresinin çeşitli kanser hücre hatları üzerinde sitotoksik etkileri
(Ankara Üniversitesi, 2022)Amaç: Bu çalışmada Arctium minus (Hill) Bernh. ssp. minus’un toprak üstü kısımlarından elde edilen metanol ekstresinin kanser hücre hatları üzerindeki sitotoksik etkilerinin değerlendirilmesi amaçlanmıştır. Gereç ve ... -
Are intervertebral disc tissue cells damaged when attempting to prevent thrombus formation using dabigatran, a new oral anticoagulant?
(Turkish Neurosurgical Society, 2019)AIM: To investigate the effect of dabigatran, a new oral anticoagulant, on human primary cell cultures isolated from intact intervertebral disc tissue. MATERIAL and METHODS: Cell cultures were prepared from tissues obtained ... -
Are specific gene expressions of extracellular matrix and nucleus pulposus affected by primary cell cultures prepared from intact or degenerative intervertebral disc tissues?
(Turkish Neurosurgical Society, 2019)AIM: To determine the gene expression patterns of nucleus pulposus (NP) in cell cultures obtained from degenerated or intact tissues. MATERIAL and METHODS: Whereas 12 of the cases were diagnosed with lumbar disc herniation ... -
Beta-sitosterol and its antinociceptive mechanism action
(University of Ankara, 2021)Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to ... -
Comparison of pediatric antibiotic prescribing practice between low and high prescribers for children in primary care
(Turkish National Pediatric Society, 2022)Background. Antibiotic prescribing is more prevalent in children. Many factors influence this practice, including the burden of outpatient visits. We aimed to compare antibiotic prescribing for children by low prescribers ... -
Çocuklarda endikasyon dışı ilaç kullanımı
(Türkiye Klinikleri, 2020)Çocukluk çağı, dinamik ve evre evre fizyolojik değişikliklerin olduğu bir dönemdir. Pediatrik popülasyonda görülen farmakokinetik ve farmakodinamik farklılıklar, ilaç kullanımı esnasında etkililik ve gü- venlilik başta ... -
Delivering growth factors through a polymeric scaffold to cell cultures containing both nucleus pulposus and annulus fibrosus
(Turkish Neurosurgical Society, 2019)AIM: To design a novel, polyvinyl alcohol (PVA)-based polymeric scaffold that permits the controlled release of insulin-like growth factor 1 (IGF-1) /bone morphogenetic protein (BMP)-2 following intervertebral disc ... -
Do we damage nucleus pulposus tissue while treating cerebrovascular ischemic neurological deficits with nimodipine?
(2018)Aim: Nimodipine is used to prevent cerebrovascular-originated ischemic neurological deficits, yet its effects on nucleus pulposus (NP) cells or annulus fibrosus (AF) cells weren’t studied. This study aimed to examine ... -
Does leukocyte-poor or leukocyte-rich platelet-rich plasma applied with biopolymers have superiority to conventional platelet-rich plasma applications on chondrocyte proliferation?
(Turkish Joint Diseases Foundation, 2017)Objectives: This study aims to investigate the possible effects of leukocyte concentration in the content of platelet-rich plasma (PRP) and the administration of PRP using a drug delivery system on chondrocyte proliferation ... -
Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1α, Chondroadherin, and COL2A1?
(Inonu University School of Medicine, 2018)Aim: In this study, it was firstly aimed to investigate the effect of Daptomycin (DAP) on the proliferation in Vancomycin (VCM)-administered primary chondrocyte cultures and non-drug-administered primary chondrocyte cultures. ... -
Dünyada ve Türkiye’de jenerik ilaç kullanımı ile ilgili gelişmeler
(2021)Jenerik ilaç, referans alınan orijinal ilaç ile aynı etkin maddeyi aynı dozda aynı ya da benzer farmasötik şekilde içeren ve orijinal ilacın patent koruma süresi bittikten sonra üretilebilen ilaçtır. 1984 yılında yürürlüğe ... -
The effects of NLR on the diagnosis and pharmacological management of brain abscesses
(Alanya Alaaddin Keykubat University, 2021)Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, ... -
Evaluation of empirical antibiotic treatment in culture negative pyogenic vertebral osteomyelitis
(Turkish Neurosurgical Society, 2019)AIM: To investigate the efficacy of empirical antibiotic treatment in culture-negative pyogenic vertebral osteomyelitis (PVO) cases. MATERIAL and METHODS: The records of patients with culture-negative PVO who were treated ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in spondylodiscitis
(2018)Aim: Spondylodiscitis, if not diagnosed on time, can cause morbidity or mortality at high rates. This study was carried out with the aim of testing the hypothesis that “neutrophil-to-lymphocyte ratio can be used” especially ... -
Evaluation of the effect of apixaban on the primary intact intervertebral disc cell cultures
(2019)Aim: Apixaban is a frequently preferred pharmacological agent in clinics to prevent deep vein thrombosis and pulmonary embolism.Such new oral anticoagulants may cause hemorrhage’s in tissues and/or organs or may cause ... -
Evaluation of the effect of daptomycin, a glycopeptide agent, on intact intervertebral disc tissue
(Turkish Neurosurgical Society, 2019)AIM: To evaluate the effects of pre- and intra-operatively administered daptomycin (DAP) on the intact human primary intervertebral disc tissue cells. MATERIAL and METHODS: Primary cell cultures were established using ... -
Evaluation of the expression and proliferation of degenerative markers in primary cell cultures obtained from human intervertebral disc tissue
(Annals of Medical Research Publishing Inc, 2020)Aim: A major cause of low back pain is disc degeneration. Nevertheless, no specific and reliable markers of the degeneration of the nucleus pulposus (NP) are available. This presented study aimed to examine changes in the ... -
In vivo wound-healing and in vitro antibacterial and antioxidant of Carduus extract
(Marmara University, 2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Turkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ... -
In vivo wound-healing and in vitro antibacterial and antioxidant properties of Carduus adpressus extract
(Marmara University, 2023)Carduus adpressus has been used for its anti-hair loss effect in traditional folk medicine. The plant species is mainly distributed in Türkiye, Bulgaria, and the Western Caucasus. The studies on this specific plant in the ...