Ara
Toplam kayıt 200, listelenen: 101-110
Potential criteria for frameworks to support the evaluation of innovative medicines in upper middle-income countries-A systematic literature review on value frameworks and multi-criteria decision analyses
(Frontiers Media SA, 2020)
Background Multicriteria Decision Analysis (MCDA), a formal decision support framework, has been growing in popularity recently in the field of health care. MCDA can support pricing and reimbursement decisions on the macro ...
Ghrelin action on GnRH neurons and pituitary gonadotropes might be mediated by GnIH-GPR147 system
(Walter De Gruyter Gmbh, 2016)
Acylated ghrelin (AG) effect on GnRH secretion is mediated, at least in part, by GH secreta-gogue receptor (GHS-R) which is present in the GnRH neurons. As the acylation is mandatory for binding to GHS-R, unacylated isoform ...
Systematic review and meta-analysis of tocilizumab therapy versus standard of care in over 15,000 COVID-19 pneumonia patients during the first eight months of the pandemic
(MDPI, 2021)
Background. Tocilizumab is an anti-IL-6 therapy widely adopted in the management of the so-called "cytokine storm" related to SARS-CoV-2 virus infection, but its effectiveness, use in relation to concomitant corticosteroid ...
Polycystic ovary syndrome: A disorder of reproductive age, its pathogenesis, and a discussion on the emerging role of herbal remedies
(Frontiers Media SA, 2022)
Polycystic ovary syndrome (PCOS) is a very common, complex, and heterogeneous endocrine disorder of women that involves a combination of environmental and genetic factors. PCOS affects women of growing age particularly at ...
The brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies
(Bentham Science Publishers, 2016)
There are rapidly replicating human data suggesting the therapeutic and neurorestorative role of repetitive transcranial magnetic stimulation (rTMS) in clinical depression. However there are only limited experimental studies ...
Reservoirs for water supply under climate change impact-A review
(Springer, 2021)
Arid region water reservoirs have different characteristics and solutions from humid regions with the most water shortage in the world socio-economically. This paper outlines possible implementation methodologies, procedures ...
Selection of renewable energy alternatives for green blockchain investments: A hybrid IT2-based fuzzy modelling
(Springer, 2021)
In this study, it is aimed to determine the most suitable renewable energy alternatives that can be used in blockchain investments. In this context, firstly, a wide literature review is made and 6 different criteria that ...
B cells and progressive multifocal leukoencephalopathy: Search for the missing link
(Frontiers Media, 2015)
Progressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease due to JC virus (JCV) replication in the brain. PML classically occurs in patients with severe immunodepression, and cases have recently ...
An integrated framework for non-traditional machining process technology selection in healthcare applications
(Strojarski Facultet, 2022)
In spite of continuous progress in technical advancement, the conventional machining process became unsatisfactory in the healthcare field due to its disadvantages. This inadequacy lead researchers to consider using the ...
Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)
Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ...