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Toplam kayıt 60, listelenen: 21-30
Potential criteria for frameworks to support the evaluation of innovative medicines in upper middle-income countries-A systematic literature review on value frameworks and multi-criteria decision analyses
(Frontiers Media SA, 2020)
Background Multicriteria Decision Analysis (MCDA), a formal decision support framework, has been growing in popularity recently in the field of health care. MCDA can support pricing and reimbursement decisions on the macro ...
Editorial: Immune-modulatory effects of vitamin D
(Frontiers Media S.A., 2020)
Vitamin D plays an essential role in bone development. However, recent studies are beginningto uncover its role as a modulator of the immune system (1). Several reports have shownassociations between vitamin D deficiency ...
Systematic review and meta-analysis of tocilizumab therapy versus standard of care in over 15,000 COVID-19 pneumonia patients during the first eight months of the pandemic
(MDPI, 2021)
Background. Tocilizumab is an anti-IL-6 therapy widely adopted in the management of the so-called "cytokine storm" related to SARS-CoV-2 virus infection, but its effectiveness, use in relation to concomitant corticosteroid ...
Bilateral oropharyngeal hairy polyps: A rare cause of dyspnea in newborns
(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2017)
Hairy polyp (HP) is one of the causes of congenital dyspnea, a rare developmental malformation of bigerminal origin that comprises both ectodermal and mesodermal elements foreign to the site in which it is found. It typically ...
Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
(MDPI, 2019)
G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family. Discovery of beta-arrestin ...
Surface modified multifunctional and stimuli responsive nanoparticles for drug targeting: Current status and uses
(MDPI, 2016)
Nanocarriers, due to their unique features, are of increased interest among researchers working with pharmaceutical formulations. Polymeric nanoparticles and nanocapsules, involving non-toxic biodegradable polymers, ...
COVID-19 vaccination and the rate of immune and autoimmune adverse events following immunization: Insights from a narrative literature review
(Frontiers Media S.A., 2022)
Despite their proven efficacy and huge contribution to the health of humankind, vaccines continue to be a source of concern for some individuals around the world. Vaccinations against COVID-19 increased the number of ...
Quest for quality in translational stroke research––a new dawn for neuroprotection?
(Multidisciplinary Digital Publishing Institute, 2022)
Despite tremendous progress in modern‐day stroke therapy, ischemic stroke remains a disease associated with a high socioeconomic burden in industrialized countries. In light of demo-graphic change, these health care costs ...
Alternative treatment method for novel coronavirus disease 2019: Coupled plasma filtration adsorption
(Aves, 2021)
Dear editor: Patients infected with severe acute respiratory syndrome corona virus 2 may have mild symptoms such as fever and cough in the early stage of this disease and these symptoms may deteriorate to acute respiratory ...
Hedgehog signaling: Linking embryonic lung development and asthmatic airway remodeling
(MDPI, 2022)
The development of the embryonic lung demands complex endodermal-mesodermal interactions, which are regulated by a variety of signaling proteins. Hedgehog (Hh) signaling is vital for lung development. It plays a key ...