Yazar "Yılmaz, İbrahim" için Scopus İndeksli Yayınlar Koleksiyonu listeleme
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Investigation of the effects of methylphenidate, an amphetamine derivative, on intervertebral disc tissue cell cultures and matrix structures
Kaya, Yasin Emre; Karaarslan, Numan; Şirin, Duygu Yaşar; Özbek, Hanefi; Kaplan, Necati; Yılmaz, İbrahim (Turkish Neurosurgical Society, 2019)AIM: To investigate the effects of methylphenidate (MPH), on intervertebral disc tissue (IVD) cell cultures and extracellular matrix structures. Changes in the expression of some important marker genes involved in anabolic ... -
Iopromide- and gadopentetic acid-derived preparates used in MR arthrography may be harmful to chondrocytes
Öznam, Kadir; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Kaya, Yasin Emre; İşyar, Mehmet; Gümüştaş, Seyit Ali; Özbek, Hanefi; Akkaya, Semih; Kayhan, Arda; Mahiroğulları, Mahir (BMC, 2017)Background: Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. ... -
Is implant washing and wound irrigation with rifampicin effective for preventing surgical site infections in lumbar instrumentation?
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Öznam, Kadir; Ateş, Özkan; Erdem, İlknur (Turkish Neurosurgical Society, 2018)AIM: To determine whether the washing of implants and autogenous bone grafts with rifampicin, and the irrigation of the surgical field using diluted rifampicin, have any significant effect on the prevention of spinal implant ... -
Is it possible to treat osteosarcoma using oligonucleotides confined into controlled release drug delivery systems?
Topuk, Savaş; Akyuva, Yener; Karaaslan, Numan; Mutlu, Çağri Ata; Yılmaz, İbrahim; İşyar, Mehmet; Şirin, Duygu Yaşar; Akkaya, Semih; Özbek, Hanefi; Mahiroğulları, Mahir (Bentham Science Publishers Ltd, 2017)Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ... -
Is there a treatment protocol in which platelet-rich plasma is effective?
Yılmaz, İbrahim; Akkaya, Semih; İşyar, Mehmet; Batmaz, Ahmet Güray; Güler, Olcay; Öznam, Kadir; Uğras, Akın; Mahiroğulları, Mahir (Elsevier Science Bv, 2016)Aim: We aimed to reveal whether there are prospective suggestions for effective and standard platelet-rich plasma applications. Methods: We searched for clinical trials and traced all the references of incorporated documents. ... -
Pharmaco-molecular assessment of the effects of anandamide and its antagonists on hippocampal tissue in Wistar albino rats
Yılmaz, İbrahim; Karaarslan, Numan; Yaşar Şirin, Duygu; Özbek, Hanefi (Verduci Editore s.r.l, 2020)OBJECTIVE: The members of the matrix metalloproteinase (MMP) family and cannabinoids (CBs) are reportedly associated with hippocampus-dependent memory functions. However, the effects of endogenously formed CBs on hippocampal ... -
Practical performance of hippocampal tissue resection in rats in pharmacomolecular research
Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi (Turkish Neurosurgical Society, 2021)AIM: To explain how to resect hippocampal tissue in rats used as live mammalian subjects for the resection of fresh cerebral tissue in laboratories.MATERIAL and METHODS: Adult male Wistar-Albino rats (n=50) were used for ... -
A practical way to prepare primer human chondrocyte culture
İşyar, Mehmet; Yılmaz, İbrahim; Şirin Yaşar, Duygu; Yalçın, Sercan; Güler, Olcay; Mahiroğulları, Mahir (Elsevier Science Bv, 2016)Biological cartilage repair is one of themost important targets for orthopedic surgeons currently. For this purpose, it is mandatory to know how to prepare a chondrocyte culture. In this study, our purpose was to introduce ... -
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
Karaarslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Özbek, Hanefi; Kaplan, Necati; Kaya, Yasin Emre; Akyuva, Yener; Gürbüz, Mehmet Sabri; Öznam, Kadir; Ateş, Özkan (Spandidos Publications Ltd, 2018)The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clinicians, exert toxic effects on human primary nucleus ... -
Q-ROF Fuzzy TOPSIS and VIKOR methods for the selection of sustainable private health insurance policies
Erdebilli, Babek; Geçer, Ebru; Yılmaz, İbrahim; Aksoy, Tamer; Hacıoğlu, Ümit; Dinçer, Hasan; Yüksel, Serhat (MDPI, 2023)As a result of the inability of people to meet their demands in the face of increasing demands, people tend to have private health insurance in addition to the general health insurance offered as a public service. Due to ... -
Safety of bioabsorbable implants in vitro
İşyar, Mehmet; Yılmaz, İbrahim; Nusran, Gürdal; Güler, Olcay; Yalçın, Sercan; Mahiroğulları, Mahir (BioMed Central, 2015)Background: The aim of the present study was to investigate the safety of bioabsorbable plates and screws in humans. Methods: For this purpose, an implant system based on [poly(lactic-co-glycolic acids)(85:15)] was designed. ... -
A study of the effects of metformin, a biguanide derivative, on annulus fibrosus and nucleus pulposus cells
Kaya, Yasin Emre; Karaarslan, Numan; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Akalan, Hande; Özbek, Hanefi (Turkish Neurosurgical Society, 2020)AIM: To investigate the effects of metformin, a drug used widely for the treatment of type 2 diabetes mellitus, on human primary cell cultures prepared from uninjured segment of disc material intervertebral disk tissues.MATERIAL ... -
Systematic evaluation of desmopressin administered to patients with aneurysmal subarachnoid hemorrhage in the light of the literature
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalışkan, Tezcan; Özbek, Hanefi; Ateş, Özkan (Turkish Neurosurgical Society, 2020)AIM: To discuss the management of patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) developing after subarachnoid hemorrhage, in a comparative manner in the light of the literature.MATERIAL ... -
Systematic evaluation of drug-loaded hydrogels for application in osteosarcoma treatment
Gümüştaş, Seyit Ali; İşyar, Mehmet; Topuk, Savaş; Yılmaz, İbrahim; Öznam, Kadir; Onay, Tolga; Ofluoğlu, Önder; Mahiroğulları, Mahir (Bentham Science Publ Ltd, 2016)This is a literature review of studies focusing on the preparation of hydrogels for use as oncological drug delivery systems in the treatment of osteosarcoma (OS). The databases of the US National Library of Medicine ... -
Systematic evaluation of promising clinical trials-gene silencing for the treatment of glioblastoma
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Topuk, Savaş; Yaşar Şirin, Duygu; Ateş, Özkan (Turkish Neurosurgical Society, 2019)AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...