Güncel Gönderiler: PubMed İndeksli Yayınlar Koleksiyonu
Toplam kayıt 4251, listelenen: 1-20
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Residues in the fructose-binding pocket are required for ketohexokinase-A activity
(2024)Excessive fructose consumption is a primary contributor to the global surges in obesity, cancer, and metabolic syndrome. Fructolysis is not robustly regulated and is initiated by ketohexokinase (KHK). In this study, we ... -
Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
(2024)Programmed death ligand 1, PD-L1 (CD274), facilitates immune evasion and exerts pro-survival functions in cancer cells. Here, we report a mechanism whereby internalization of PD-L1 in response to alterations of bioactive ... -
Versatile vertical alar resection technique for positioning of the nasal tip
(2024)Background: In rhinoplasty, it is very important to adjust the rotation and projection of the tip together harmoniously with the nasal dorsum and face to achieve pleasing results. Objective: In this study, our aim is to ... -
Influence of endodontic access cavity design on mechanical properties of a first mandibular premolar tooth: a finite element analysis study
(2024)Objectives: This study aimed to investigate the influence of access cavity designs on the mechanical properties of a single-rooted mandibular first premolar tooth under various static loads using a finite element analysis. ... -
I-BaR: integrated balance rehabilitation framework
(2024)Neurological diseases are observed in approximately 1 billion people worldwide. A further increase is foreseen at the global level as a result of population growth and aging. Individuals with neurological disorders often ... -
Factors affecting mortality in covid-19-associated pulmonary aspergillosis: an international ID-IRI study
(2024)Background: This study aimed to identify factors that influence the mortality rate of patients with coronavirus disease (COVID-19)-associated pulmonary aspergillosis (CAPA). Methods: In this cross-sectional study, data ... -
Evaluation of seizure semiology, genetics, magnetic resonance imaging, and electroencephalogram findings in children with rett syndrome: a multicenter retrospective study
(2024)Objectives: This study aimed to evaluate seizure semiology, electroencephalogram (EEG), magnetic resonance imaging (MRI), and genetic findings, as well as treatment choices in Rett syndrome (RTT). Methods: A retrospective ... -
Lungbank: a novel biorepository strategy tailored for comprehensive multiomics analysis and p-medicine applications in lung cancer
(2024)Background/aim: LUNGBANK was established as part of Project LUNGMARK, pioneering a biorepository dedicated exclusively to lung cancer research. It employs cutting-edge technologies to streamline the handling of biospecimens, ... -
Synthesis and anticancer activity of novel indole derivatives as dual EGFR/SRC kinase inhibitors
(2024)Background: Recent studies showed that the cooperation between c-SRC and EGFR is responsible for more aggressive phenotype in diverse tumors, including glioblastomas and carcinomas of the colon, breast, and lung. Studies ... -
Effects of various laser treatments on surface characterization and repair bond strength of zirconia-reinforced lithium silicate ceramics
(2024)Purpose: To evaluate the effects of two different lasers and their use in combination with hydrofluoric acid (HF) etching on the surface roughness of zirconia-reinforced lithium silicate (ZLS) ceramics and their shear bond ... -
Comparison of wear and fracture resistance of additively and subtractively manufactured screw-retained, implant-supported crowns
(2024)Statement of problem. Additively manufactured resins indicated for fixed definitive prostheses have been recently marketed. However, knowledge on their wear and fracture resistance when fabricated as screw-retained, ... -
Effects of myofascial release technique in patients with unilateral cervical radiculopathy: A single blind-randomized clinical trial
(2024)Objective: The aim of this study was to investigate the effectiveness of the myofascial release technique in individuals diagnosed with unilateral cervical radiculopathy. Materials and methods: Thirty-four cervical ... -
Short-term azithromycin use is associated with QTc interval prolongation in children with cystic fibrosis
(2024)Background: Azithromycin is used for children with cystic fibrosis (CF) for its immunomodulatory and antiinflammatory action. This study investigated the short-term alterations in QTc interval associated with azithromycin ... -
Correction: Altered blood parameters in "major depression" patients receiving repetitive transcranial magnetic stimulation (rTMS) therapy: a randomized case-control study
(2024)Correction to: Translational Psychiatryhttps://doi.org/10.1038/s41398-024-02942-8, published online 25 June 2024 In this article, the order that the authors appeared in the author list was incorrect. The original article ... -
Is SWEEPS better than PUI in reducing intracanal bacteria and inflammation in cases of apical periodontitis?
(2024)To evaluate the efficacy of SWEEPS mode of the Er: YAG laser(SL) and passive ultrasonic irrigation(PUI) in the eradication of microorganisms and in the inflammation detection by IL-1β. Thirty patients with chronic apical ... -
Patterns and trends in continuous glucose monitoring utilization among commercially insured individuals with type 1 diabetes: 2010-2013 to 2016-2019
(2024)Prior studies suggest that only ∼30% of patients with type 1 diabetes use continuous glucose monitoring (CGM), but most studies to date focused on children and young adults seen by endocrinologists or in academic centers. ... -
Hijacking limitations of working memory load to test for composition in language
(2024)Although language depends on storage and composition, just what is stored or (de)composed remains unclear. We leveraged working memory load limitations to test for composition, hypothesizing that decomposed forms should ... -
Smoking affects global and regional brain entropy in depression patients regardless of depression: preliminary findings
(2024)Objective: This study examines the effect of smoking on global and regional brain entropy in patients with Major Depressive Disorder (MDD), aiming to elucidate the relationship between smoking habits and brain network ... -
Rolle von parametern bei der vollblutanalyse als indikator für systemische entzündungen bei kindern mit rheumatischen klappenerkrankungen
(2024)Zusammenfassung Zweck: Die wichtigste Ursache für Mortalität und Morbidität bei akutem rheumatischem Fieber (ARF) sind Karditis und rheumatische Herzkrankheit (RHD). Ziel dieser Studie war es, Marker zu identifizieren, die ...
