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Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases
(Elsevier Inc., 2023)
Background: Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are associated with metabolic abnormalities. Integrative analysis of human clinical data and animal studies ...
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: A randomised, double-blinded, placebo-controlled phase-II trial
(BioMed Central Ltd, 2023)
Background: Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed ...
Brain temperature in healthy and diseased conditions: A review on the special implications of MRS for monitoring brain temperature
(Elsevier Masson s.r.l., 2023)
Brain temperature determines not only an individual's cognitive functionality but also the prognosis and mortality rates of many brain diseases. More specifically, brain temperature not only changes in response to different ...
Neuroimaging-guided transcranial magnetic and direct current stimulation in MCI: Toward an individual, effective and disease-modifying treatment
(SAGE Publications Inc, 2023)
The therapeutic approaches currently applied in Alzheimer's disease (AD) and similar neurodegenerative diseases are essentially based on pharmacological strategies. However, despite intensive research, the effectiveness ...
The effect of Electromyography (EMG)-driven Robotic Treatment on the recovery of the hand Nine years after stroke
(Hanley and Belfus Inc., 2023)
Objective: To investigate the effect of electromyography (EMG)-driven robotic therapy on the recovery of the hand in a stroke case lasting 9 years.Case: An 18-year-old patient with hemiparesis due to the ischemic lesion ...
The savant syndrome: a gift or a disability? A deeper look into metabolic correlates of hidden cognitive capacity
(Bentham Science Publishers, 2023)
Savant syndrome is a rare and unusual condition that occurs in the presence of severe developmental disabilities, disorders, and injuries. The syndrome can be congenital from birth to childhood or acquired as a result of ...
The effects of repetitive transcranial magnetic stimulation and aerobic exercise on cognition, balance and functional brain networks in patients with Alzheimer's disease
(Springer, 2023)
The purpose of this study was to investigate the effects of high-frequency repetitive Transcranial Magnetic Stimulation (rTMS) and aerobic exercises (AE) in addition to the pharmacological therapy (PT) in Alzheimer's Disease ...
Alterations of resting-state Gamma frequency characteristics in aging and Alzheimer's disease
(Springer, 2023)
Alzheimer's disease (AD) is an important brain disease associated with aging. It involves various functional and structural changes which alter the EEG characteristics. Although numerous studies have found changes in delta, ...
Relationship between default mode network and resting-state electroencephalographic alpha rhythms in cognitively unimpaired seniors and patients with dementia due to Alzheimer's disease
(Oxford University Press Inc., 2023)
Here we tested the hypothesis of a relationship between the cortical default mode network (DMN) structural integrity and the resting state electroencephalographic (rsEEG) rhythms in patients with Alzheimer's disease with ...
Differentiation of claustrum resting-state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease
(Wiley, 2023)
The claustrum is a sheet-like of telencephalic gray matter structure whose function is poorly understood. The claustrum is considered a multimodal computing network due to its reciprocal connections with almost all cortical ...