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Toplam kayıt 52, listelenen: 41-50
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases
(Elsevier Inc., 2023)
Background: Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are associated with metabolic abnormalities. Integrative analysis of human clinical data and animal studies ...
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: A randomised, double-blinded, placebo-controlled phase-II trial
(BioMed Central Ltd, 2023)
Background: Alzheimer’s disease (AD) is associated with metabolic abnormalities linked to critical elements of neurodegeneration. We recently administered combined metabolic activators (CMA) to the AD rat model and observed ...
Neuroimaging-guided transcranial magnetic and direct current stimulation in MCI: Toward an individual, effective and disease-modifying treatment
(SAGE Publications Inc, 2023)
The therapeutic approaches currently applied in Alzheimer's disease (AD) and similar neurodegenerative diseases are essentially based on pharmacological strategies. However, despite intensive research, the effectiveness ...
Quantitative evaluation of brain volumes in drug-free major depressive disorder using MRI-Cloud method
(Lippincott Williams & Wilkins, 2021)
Background Quantitative analysis of the high-resolution T1-weighted images provides useful markers to measure anatomical changes during brain degeneration related to major depressive disorder (MDD). However, there are ...
Therapeutic role of repetitive transcranial magnetic stimulation in Alzheimer's and Parkinson's disease: Electroencephalography microstate correlates
(Frontiers Media SA, 2022)
Introduction: The microstate analysis is a method to convert the electrical potentials on the multi-channel electrode array to topographical electroencephalography (EEG) data. Repetitive transcranial magnetic stimulation ...
The savant syndrome: a gift or a disability? A deeper look into metabolic correlates of hidden cognitive capacity
(Bentham Science Publishers, 2023)
Savant syndrome is a rare and unusual condition that occurs in the presence of severe developmental disabilities, disorders, and injuries. The syndrome can be congenital from birth to childhood or acquired as a result of ...
Differentiation of claustrum resting-state functional connectivity in healthy aging, Alzheimer's disease, and Parkinson's disease
(Wiley, 2023)
The claustrum is a sheet-like of telencephalic gray matter structure whose function is poorly understood. The claustrum is considered a multimodal computing network due to its reciprocal connections with almost all cortical ...
A structural and resting-state functional connectivity investigation of the pulvinar in elderly individuals and Alzheimer's disease patients
(John Wiley and Sons Inc, 2023)
In Alzheimer's disease (AD), structural and functional changes in the brain may give rise to disruption of specific cognitive functions. The aim of this study is to investigate the functional connectivity alterations in ...
EGb 761 reduces Ca2+ influx and apoptosis after pentylenetetrazole treatment in a neuroblastoma cell line
(Frontiers Media SA, 2023)
Background: Transient receptor potential (TRP) channels have been found to have significant implications in neuronal outgrowth, survival, inflammatory neurogenic pain, and various epileptogenic processes. Moreover, there ...
Infection with COVID-19 is no longer a public emergency: But what about degenerative dementia?
(John Wiley and Sons Inc, 2023)
Although no longer considered a public health threat, post-COVID cognitive syndrome continues to impact on a considerable proportion of individuals who were infected with COVID-19. Recent studies have also suggested that ...