Kurum Yazarı "Tok, Olgu Enis" Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed İçin Listeleme
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The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
Söylemez, Esra; Özçağlı, Eren; Korkmaz, Serol; Tok, Olgu Enis; Aydın, Mehmet Şerif; Omurtag, Gülden Zehra (SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Cannabidiol as a potential novel treatment for endometriosis by its anti-inflammatory, antioxidative and antiangiogenic effects in an experimental rat model
Ökten, Sabri Berkem; Çetin, Çağlar; Tok, Olgu Enis; Güler, Eray Metin; Taha, Sevde Havva; Özcan, Pınar; Fıçıcıoğlu, Cem (Elsevier Science Ltd, 2023)Research question: Can cannabidiol (CBD) be used in the treatment of endometriosis for its anti-inflammatory, antioxidative and antiangiogenic effects? Design: Endometrial implants were surgically induced in 36 female ... -
Comparative effects of the antioxidant glutathione with metformin and Diane-35 on hormonal, metabolic, and inflammatory indicators in a DHEA-induced PCOS rat model
Coşar, Aslı; Özcan, Pınar; Tanoğlu, Fatma Başak; Tok, Olgu Enis; Özkara, Gülçin; Timur, Hikmet Tunç; Çetin, Çağlar; Neccar, Duygu (Taylor and Francis Ltd., 2024)Objective: Comparison of hormonal, metabolic and inflammatory markers of glutathione with metformin and Diane-35 in a rat model of PCOS induced by dehydroepiandrosterone.Methods: Twenty-five female rats were randomized ... -
Comparison of 3 cell-free matrix scaffolds used to treat osteochondral lesions in a rabbit model
Demir, Ahder İrem; Pulatkan, Anıl; Uçan, Vahdet; Yılmaz, Bengi; Tahmasebifar, Aydın; Tok, Olgu Enis; Tuncay, İbrahim; Elmalı, Nurzat; Öztürk, Burak Yağmur; Uzer, Gökçer (SAGE Publications Inc., 2022)Background: Various cell-free scaffolds are already in use for the treatment of osteochondral defects (OCDs); however, a gold standard material has not yet been defined. Purpose: This study compared the macroscopic, ... -
Culturing, freezing, processing, and imaging of entire organoids and spheroids while still in a hydrogel
Tok, Olgu Enis; Demirel, Gamze; Saatçi, Yusuf; Akbulut, Zeynep; Kayalar, Özgecan; Aktaş, Ranan Gülhan (Journal of Visualized Experiments, 2022)Organoids and spheroids, three-dimensional growing structures in cell culture labs, are becoming increasingly recognized as superior models compared to two-dimensional culture models, since they mimic the human body better ... -
Effects of melatonin on both testicular regeneration and recovery of spermatogenesis in busulfan-treated rats
Taşlıdere, Elif; Eşrefoğlu, Mukaddes; Tok, Olgu Enis; Taşlıdere, Bahadır; Bulut, Huri (Faculdade de Ciencias Farmaceuticas (Biblioteca), 2022)Testicular damage is one of the most hazardous effects of chemotherapy as it is frequently associated with oligozoospermia and azoospermia. This study aimed at evaluating the protective effect of melatonin in a rat model ... -
The effects of transcranial focused ultrasound stimulation of nucleus accumbens on neuronal gene expression and brain tissue in high alcohol-preferring rats
Deveci, Erdem; Akbaş, Fahri; Ergün, Arif Şanlı; Kurtulmuş, Ayşe; Koçak, Ali Barlas; Boyraz, Rabia Kevser; Tok, Olgu Enis; Aydın, Mehmet Şerif; Kılıç, Özge; Bozkurt, Ayhan; Uysal, Ömer; Eşrefoğlu, Mukaddes (Springer, 2023)We investigated the effect of low-intensity focused ultrasound (LIFU) on gene expression related to alcohol dependence and histological effects on brain tissue. We also aimed at determining the miRNA-mRNA relationship and ... -
New bone-generative effect of Salvia officinalis L. in the expanded midpalatal suture An in vivo and in vitro study
Kayalar, Emre; Göger, Fatih; Taş Deynek, Gül; Tok, Olgu Enis; Küçük, Sevim (Urban & Vogel, 2022)Purpose The aims of this study were to evaluate the effects of systemic administration of Salvia officinalis Linnaeus (L.) leaf extract on new bone formation in the expanded premaxillary suture in rats in vivo and to examine ... -
Protective effect of glutathione administration on ovarian function in female rats with cyclophosphamide-induced ovarian damage
Yurttançıkmaz, Ebru Tansu; Özcan, Pınar; Tanoğlu, Fatma Başak; Tok, Olgu Enis; Timur, Hikmet Tunç; Çetin, Çağlar (2024)Objectives: We investigated the potential of glutathione to protect ovarian function in rats exposed to cyclophosphamide by measuring serum anti-Mullerian hormone (AMH) levels, follicle counts, and related parameters. ... -
Treatment of ovarian damage induced by chemotherapeutic drugs in female rats with G-CSF and platelet-rich plasma(PRP): An immunohistochemical study correlation with novel marker INSL-3
Çetin, Çağlar; Ökten, Sabri Berkem; Tok, Olgu Enis; Özcan, Pınar; Gökmen Karasu, Ayşe Filiz; Tanoğlu, Fatma Başak; Taha, Havva Sevde; Ateş, Seda (Taylor and Francis Ltd., 2024)Objective: To assess the impacts of Platelet-Rich Plasma(PRP) and Granulocyte Colony-Stimulating Factor(G-CSF) on a rat model with induced ovarian follicular damage caused by cyclophosphamide(Cy).Materials and Methods: ...