Browsing Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed by Author "Fadl, Samar"
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Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro
Ferreira, Juliana C.; Fadl, Samar; İlter, Metehan; Pekel, Hanife; Rezgui, Rachid; Şensoy, Özge; Rabeh, Wael M. (John Wiley and Sons Inc, 2021)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19), one of the most challenging global pandemics of the modern era. Potential treatment strategies against ... -
Residues in the fructose-binding pocket are required for ketohexokinase-A activity
Ferreira, Juliana C.; Villanueva, Adrian J.; Fadl, Samar; Al Adem, Kenana; Cinviz, Zeynep Nur; Nedyalkova, Lyudmila; Cardoso, Thyago H.S.; Andrade, Mario Edson; Saksena, Nitin K.; Şensoy, Özge; Rabeh, Wael M. (2024)Excessive fructose consumption is a primary contributor to the global surges in obesity, cancer, and metabolic syndrome. Fructolysis is not robustly regulated and is initiated by ketohexokinase (KHK). In this study, we ...