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dc.contributor.authorÜstündağ, Ünsal Veli
dc.contributor.authorEmekli Alturfan, Ebru
dc.date.accessioned2020-01-20T13:54:43Z
dc.date.available2020-01-20T13:54:43Z
dc.date.issued2020en_US
dc.identifier.citationÜstündağ, Ü. V. ve Emekli Alturfan, E. (2020). Wnt pathway: A mechanism worth considering in endocrine disrupting chemical action. Toxicology and Industrial Health, 36(1), 41-53. https://doi.org/10.1177/0748233719898989en_US
dc.identifier.issn0748-2337
dc.identifier.issn1477-0393
dc.identifier.urihttps://doi.org/10.1177/0748233719898989
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4905
dc.description.abstractEndocrine disrupting chemicals (EDCs) are defined as exogenous substances that can alter the development and functioning of the endocrine system. The Wnt signaling pathway is an evolutionarily conserved pathway consisting of proteins that transmit cell-to-cell receptors through cell surface receptors, regulating important aspects of cell migration, polarity, neural formation, and organogenesis, which determines the fate of the cell during embryonic development. Although the effects of EDCs have been studied in terms of many molecular mechanisms; because of its critical role in embryogenesis, the Wnt pathway is of special interest in EDC exposure. This review provides information about the effects of EDC exposure on the Wnt/β-catenin pathway focusing on studies on bisphenol A, di-(2-ethylhexyl) phthalate, diethylstilbestrol, cadmium, and 2,3,7,8-tetrachlorodibenzo-p-dioxin.en_US
dc.language.isoengen_US
dc.publisherSAGE Publications Ltd.en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEndocrine Disrupting Chemicalen_US
dc.subjectWnt Signaling Pathwayen_US
dc.subjectBisphenol Aen_US
dc.subjectPhthalateen_US
dc.titleWnt pathway: A mechanism worth considering in endocrine disrupting chemical actionen_US
dc.typearticleen_US
dc.relation.ispartofToxicology and Industrial Healthen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalıen_US
dc.authorid0000-0003-0804-1475en_US
dc.identifier.volume36en_US
dc.identifier.issue1en_US
dc.identifier.startpage41en_US
dc.identifier.endpage53en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1177/0748233719898989en_US
dc.identifier.wosqualityQ3en_US
dc.identifier.scopusqualityQ2en_US


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