Show simple item record

dc.contributor.authorSezgin Özcan, Didem
dc.contributor.authorDalyan, Meltem
dc.contributor.authorErgül, Serhat
dc.contributor.authorÜnsal Delialioğlu, Sibel
dc.contributor.authorKöseoğlu, Belma Füsun
dc.identifier.citationSezgin Özcan, D., Dalyan, M., Ergül, S., Ünsal Delialioğlu, S. ve Köseoğlu, B. F. (2019). Evaluation of vitamin D levels in patients with breast cancer-related lymphedema: An observational cross-sectional study. Turkish Journal of Osteoporosis, 25(3), 105-110.
dc.description.abstractObjective: The aim of our study was to compare plasma vitamin D levels between patients with breast cancer-related lymphedema (BCRL) and healthy population, and also to investigate the effects of socio-demographic and clinical factors and lymphedema severity on vitamin D levels. Materials and Methods: Eighty patients with BCRL [mean age 55.5 +/- 8.9 (36-81)] and age- and sex-matched 80 healthy controls [mean age 53.7 +/- 7.4 (32-70)] who were not on calcium or vitamin D supplementation were included in the study. Socio-demographic and clinical characteristics of the subjects were questioned. Plasma 25-Hydroxyvitamin D3, calcium, phosphorus, alkaline phosphatase (ALP), and parathormone (PTH) levels were evaluated. Lymphedema was classified as stage 0, I, II, or III. Results: The mean duration of lymphedema was 23.5 +/- 13.8 months. Comparisons revealed lower vitamin D levels and higher PTH and ALP levels in patients with BCRL than healthy controls. As a result of multivariate regression analysis, a significant relationship was revealed between vitamin D levels and age, breast cancer stage, and disease duration in patients with BCRL. Vitamin D levels were significantly lower and PTH levels were significantly higher in stage 3 lymphedema patients compared to stage 1. Conclusion: Vitamin D levels were detected lower in patients with lymphedema than healthy controls. Although vitamin D levels were found to be lower in patients with severe lymphedema, the multivariate regression analysis revealed that the severity of lymphedema does not have a significant effect on vitamin D levels.en_US
dc.publisherGalenos Yayıncılıken_US
dc.rightsAttribution NonCommercial 4.0 International*
dc.subjectVitamin Den_US
dc.subjectBreast Canceren_US
dc.titleEvaluation of vitamin D levels in patients with breast cancer-related lymphedema: An observational cross-sectional studyen_US
dc.relation.journalTurkish Journal of Osteoporosisen_US
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Fakültesi, Fizyoterapi ve Rehabilitasyon Bölümüen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US

Files in this item


This item appears in the following Collection(s)

Show simple item record

Except where otherwise noted, this item's license is described as info:eu-repo/semantics/openAccess