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dc.contributor.authorKaradağ, Ayşe Esra
dc.contributor.authorDemirci, Betül
dc.contributor.authorÇeçen, Ömer
dc.contributor.authorTosun, Fatma
dc.date.accessioned2019-12-31T07:33:17Z
dc.date.available2019-12-31T07:33:17Z
dc.date.issued2019en_US
dc.identifier.citationKaradağ, A. E., Demirci, B., Çeçen, Ö. ve Tosun, F. (2019). Chemical characterization of Glaucosciadium cordifolium (Boiss.) B. L. Burtt & P. H. Davis essential oils and their antimicrobial, and antioxidant activities. Istanbul Journal of Pharmacy, 49(2), 77-80. https://doi.org/10.26650/IstanbulJPharm.2019.19013en_US
dc.identifier.issn0367-7524
dc.identifier.issn2548-0731
dc.identifier.urihttps://doi.org/10.26650/IstanbulJPharm.2019.19013
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4827
dc.description.abstractChemical composition of volatile oils obtained from the roots, fruits and aerial parts of Glaucosciadium cordifolium (Boiss.) B. L. Burtt& P. H. Davis (Apiaceae) were analyzed using gas chromatography-flame ionization detector/mass spectrometry, simultaneously. Furthermore, antimicrobial and antioxidant activities of G. cordifolium volatile oils were investigated for possible utilization. Total of 62 volatile compounds were identified in G. cordifolium essential oils, where the main component was characterized as alpha-pinene in all parts, commonly. The other main components were beta-pinene (15.7%), (Z)-beta-ocimene (14%) and sabinene (7%) in the volatile oil of the aerial part; sabinene (10.1%), beta-pinene (10.1%) and alpha-phellandrene (5.3%) in the essential oil of the fruits; hexadecane (12.2%), tetradecane (11.9%), octadecane (7.4%) in the essential oil obtained from the root, respectively. The in vitro microdilution method was used for the antimicrobial activity testing against Salmonella typhi ATCC 6539, Acinetobacter baumanii ATCC 19606, Bacillus cereus ATCC 14579, Staphylococcus aereus ATCC 6538, Listeria monocytogenes ATCC 19115, Helicobacter pylori ATCC 43504 and Mycobacterium avium ATCC 25291. The best antimicrobial activity of the volatile oils was against L. monocytogenes among the tested microorganisms. In addition, DPPH center dot-ABTS(center dot) scavenging activity was tested, none of the essential oils showed any significant antioxidant activity.en_US
dc.language.isoengen_US
dc.publisherIstanbul Universityen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectApiaceaeen_US
dc.subjectGlaucosciadium Cordifoliumen_US
dc.subjectAntimicrobialen_US
dc.subjectAntioxidanten_US
dc.subjectGas Chromatographyen_US
dc.subjectMass Specrometryen_US
dc.titleChemical characterization of Glaucosciadium cordifolium (Boiss.) B. L. Burtt & P. H. Davis essential oils and their antimicrobial, and antioxidant activitiesen_US
dc.typearticleen_US
dc.relation.journalIstanbul Journal of Pharmacyen_US
dc.departmentİstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmakognozi Ana Bilim Dalıen_US
dc.authorid0000-0002-3412-0807en_US
dc.authorid0000-0003-2533-5141en_US
dc.identifier.volume49en_US
dc.identifier.issue2en_US
dc.identifier.startpage77en_US
dc.identifier.endpage80en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.26650/IstanbulJPharm.2019.19013en_US


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