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dc.contributor.authorYalçınkaya Kalyan, Ender
dc.contributor.authorCan Çelik, Seren
dc.contributor.authorOkan, Özlem
dc.contributor.authorAkdeniz, Gülden
dc.contributor.authorKarabulut, Seda
dc.contributor.authorÇalışkan, Eray
dc.date.accessioned2019-12-30T09:06:32Z
dc.date.available2019-12-30T09:06:32Z
dc.date.issued2019en_US
dc.identifier.citationYalçınkaya Kalyan, E., Can Çelik, S., Okan, Ö., Akdeniz, G., Karabulut, S. ve Çalışkan, E. (2019). Does a microfluidic chip for sperm sorting have a positive add-on effect on laboratory and clinical outcomes of intracytoplasmic sperm injection cycles? A sibling oocyte study. Andrologia, 51(10). https://doi.org/10.1111/and.13403en_US
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.urihttps://doi.org/10.1111/and.13403
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4795
dc.description.abstractThe most recent technologies for sperm sorting involve microfluidics. However, the most important question whether their use is of any advantage in terms of laboratory and clinical IVF/ICSI outcomes still remains controversy. In this study, we aimed to investigate whether a microfluidic sperm sorting device (Fertile Plus (R)) has a positive add-on effect on laboratory and clinical outcomes. Sibling oocytes of 81 patients were assigned to two sperm sorting groups including swim up and Fertile Plus (R). All embryos were cultured until day 5/6. Fertilisation, embryo quality and blastocyst development were assessed as primary outcomes among 81 patients; clinical pregnancy, implantation and live birth rates were analysed as secondary outcomes as a subgroup analysis due to transfer cancellations. No statistically significant differences were found between groups in terms of all outcomes analysed in laboratory and clinical terms (p > .05 for all). The results of this study suggest that sorting spermatozoa through Fertile chip does not improve laboratory outcomes significantly and does not seem to have a positive contribution to clinical outcomes.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChipen_US
dc.subjectImplantationen_US
dc.subjectIntracytoplasmic Sperm Injectionen_US
dc.subjectMicrofluidicen_US
dc.subjectSiblingen_US
dc.titleDoes a microfluidic chip for sperm sorting have a positive add-on effect on laboratory and clinical outcomes of intracytoplasmic sperm injection cycles? A sibling oocyte studyen_US
dc.typearticleen_US
dc.relation.ispartofAndrologiaen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)en_US
dc.authorid0000-0003-3302-5004en_US
dc.identifier.volume51en_US
dc.identifier.issue10en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1111/and.13403en_US
dc.identifier.wosqualityQ3en_US
dc.identifier.scopusqualityQ2en_US


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