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dc.contributor.authorArslan, Naciye Çiğdem
dc.contributor.authorDeğirmenci, Ali Kadir
dc.contributor.authorÖzdenkaya, Yaşar
dc.contributor.authorTerzi, Cem
dc.date.accessioned2019-12-30T08:32:06Z
dc.date.available2019-12-30T08:32:06Z
dc.date.issued2020en_US
dc.identifier.citationArslan, N. Ç., Değirmenci, A. K., Özdenkaya, Y. ve Terzi, C. (2020). Wound irrigation with chlorhexidine gluconate reduces surgical site infection in pilonidal disease: Single-blind prospective study. Surgical Infections, 21(2), 143-149. https://doi.org/ 10.1089/sur.2019.053en_US
dc.identifier.issn1096-2964
dc.identifier.issn1557-8674
dc.identifier.urihttps://doi.org/ 10.1089/sur.2019.053
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4792
dc.description.abstractBackground: The aim of this study was to determine whether incision irrigation with chlorhexidine gluconate (CHG) reduces surgical site infections (SSIs) in pilonidal disease surgery. Methods: Between 2013 and 2018, patients who underwent wide excision with primary closure for pilonidal disease were enrolled in this prospective observational multi-institutional cohort. The incision was irrigated with either saline or 0.05% CHG before skin closure. The infection risk of each patient was determined by the National Nosocomial Infection Surveillance System. Post-operative site care and follow-up were carried out according to the U.S. Centers for Disease Control and Prevention guideline by two surgeons blinded to the irrigation solution used. Surgical site infection rates in the saline and 0.05% CHG groups were compared. The secondary outcomes were seroma formation, incision dehiscence, and time to healing. Results: There were 129 patients in the control group and 138 patients in the CHG group. The mean age was 25.1 +/- 5.4, and 225 patients (84.3%) were male. Surgical site infection was seen in 35 patients (13.1%): 26 (20.2%) in the control group and 9 (6.5%) in the CHG group (p = 0.001). There were no differences in seroma formation (n = 12; 9.3% in the control vs n = 12; 8.7% in the CHG group; p = 0.515) or incision dehiscence (n = 9; 7% in the control vs n = 9; 6.5% in the CHG group; p = 0.537). The primary healing rate was higher in the CHG group (n = 130; 94.2%) than in the control group (n = 104; 80.6%). Time to healing was 20.5 +/- 7.8 days in the control group and 16 +/- 4.3 days in the CHG group (p < 0.001). Conclusion: Intra-operative incision irrigation with CHG decreased the SSI rate and time to healing in pilonidal disease surgery. Further randomized trials should focus on specific irrigation methods and procedures to build a consensus on the effect of incision irrigation on SSIs.en_US
dc.language.isoengen_US
dc.publisherMary Ann Lieberten_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChlorhexidine Gluconateen_US
dc.subjectPilonidal Diseaseen_US
dc.subjectSurgical Site Infectionen_US
dc.titleWound irrigation with chlorhexidine gluconate reduces surgical site infection in pilonidal disease: Single-blind prospective studyen_US
dc.typearticleen_US
dc.relation.ispartofSurgical Infectionsen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalıen_US
dc.authorid0000-0002-2282-7207en_US
dc.authorid0000-0003-0428-2511en_US
dc.identifier.volume21en_US
dc.identifier.issue2en_US
dc.identifier.startpage143en_US
dc.identifier.endpage149en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1089/sur.2019.053en_US
dc.identifier.wosqualityQ3en_US
dc.identifier.scopusqualityQ2en_US


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