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dc.contributor.authorÖzdenkaya, Yaşar
dc.contributor.authorÖlmüşçelik, Oktay
dc.contributor.authorBasım, Pelin
dc.contributor.authorSaka, Burcu
dc.contributor.authorArslan, Naciye Çiğdem
dc.date.accessioned2019-12-26T05:52:11Z
dc.date.available2019-12-26T05:52:11Z
dc.date.issued2019en_US
dc.identifier.citationÖzdenkaya, Y., Ölmüşçelik, O., Basım, P., Saka, B. ve Arslan, N. Ç. (2019). The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats. Acta Cirurgica Brasileira, 34(8). http://doi.org/10.1590/s0102-865020190080000001en_US
dc.identifier.issn0102-8650
dc.identifier.urihttp://doi.org/10.1590/s0102-865020190080000001
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4703
dc.description.abstractPurpose: To evaluate the effect of fibrin glue on staple-line leak after sleeve gastrectomy. Methods: Fourteen adult wistar rats 300 gr were randomized into two groups: Control group (n=7) and study group (n=7). All the rats underwent sleeve gastrectomy using lineer stapler. In the study group, fibrin glue was used to reinforce the staple-line. The rats were sacrificed 7 days after surgery. The stomach was resected, submerged in saline and exposed to excess pressure to obtain a burst pressure value. The gastric staple line was evaluated histopathologically according to the Ehrlich Hunt scale. The results of the two groups were compared. Results: The mean Ehrlich-Hunt scores for inflammation, fibroblastic activity and neo-angiogenesis were similar between the groups (p>0.05). Collagen deposition was significantly higher in study group (3.42±0.53) when compared with control group (2.57±0.78) (p=0.035). The mean burst pressure was 137.8±8.5 mmHg for control group and 135.0±8.1 mmHg for study group (p=0.536). Conclusion: Reinforcement of the staple-line with fibrin glue has no effect on the burst pressure after sleeve gastrectomy. More studies are needed to evaluate the precautions against leak after sleeve gastrectomy.en_US
dc.language.isoengen_US
dc.publisherOciedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgiaen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.en*
dc.subjectFibrin Tissue Adhesiveen_US
dc.subjectGastrectomyen_US
dc.subjectRatsen_US
dc.titleThe effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in ratsen_US
dc.typearticleen_US
dc.relation.journalActa Cirurgica Brasileiraen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Patoloji Ana Bilim Dalıen_US
dc.authorid0000-0003-0428-2511en_US
dc.authorid0000-0002-9815-1848en_US
dc.authorid0000-0002-9452-9276en_US
dc.authorid0000-0001-6830-7701en_US
dc.authorid0000-0002-2282-7207en_US
dc.identifier.volume34en_US
dc.identifier.issue8en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1590/s0102-865020190080000001en_US


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