ORCID "0000-0002-9354-0000" Makale Koleksiyonu için listeleme
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Effects of foeniculum vulgare essential oil compounds, fenchone and limonene, on experimental wound healing
Keskin, İlknur; Günal, Mehmet Yalçın; Ayla, Şule; Kolbaşı, Bircan; Sayın Şakul, Arzu Ayşe; Kılıç, Ülkan; Gök, Özlem; Köroğlu, Kutay M.; Özbek, Hanefi (Taylor and Francis Ltd, 2017)We investigated the wound healing efficacy of the Foeniculum vulgare compounds, fenchone and limonene, using an excisional cutaneous wound model in rats. An excision wound was made on the back of the rat and fenchone and ... -
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury
Şakul, Ayşe Arzu; Balçıkanlı, Zeynep; Ateş Özsoy, Nilay; Orhan, Cemal; Şahin, Nurhan; Tuzcu, Mehmet; Juturu, Vijaya; Kılıç, Ertuğrul; Şahin, Kazım (John Wiley and Sons Inc, 2024)A novel curcumin formulation increases relative absorption by 46 times (CurcuWIN®) of the total curcuminoids over the unformulated standard curcumin form. However, the exact mechanisms by which curcumin demonstrates its ... -
Investigation of the effect of adalimumab on experimental brain injury in mice
Günal, Mehmet Yalçın; Çankaya, Seyda; Tönük, Şükrü Burak; Özdemir, Ekrem Musa; Sayın Şakul, Ayşe Arzu (2019)Aim: We aimed to investigate the neuroprotective role of adalimumab based on the hypothesis that "TNF-alpha inhibitor adalimumab may affect inflammationrelated neuronal injury due to its anti-inflammatory effect". Methods: ... -
Protective effect of lutein/zeaxanthin isomers in traumatic brain injury in mice
Günal, Mehmet Yalçın; Şakul, Ayşe Arzu; Çağlayan, Ahmet Burak; Erten, Füsun; Durmaz Kurşun, Öznur Ece; Kılıç, Ertuğrul; Şahin, Kazım (Springer, 2021)Previous studies revealed that oxidative stress and inflammation are the main contributors to secondary injury after traumatic brain injury (TBI). In an earlier study, we reported that lutein/zeaxanthin isomers (L/Zi) exert ... -
Squalene attenuates the oxidative stress and activates AKT/mTOR pathway against cisplatin-induced kidney damage in mice
Sakul, Arzu; Ozansoy, Mehmet; Elibol, Birsen; Ayla, Şule; Günal, Mehmet Yalçın; Yozgat, Yasemin; Basağa, Hüveyda; Şahin, Kazım; Kazancıoğlu, Rümeyza; Kılıç, Ulkan (Tubitak Scientific & Technical Research Council Turkey, 2019)The clinical use of cisplatin, which is a first-line anticancer agent, is highly restricted due to its adverse effects on kidneys that lead to nephrotoxicity. Therefore, some potential reno-protective substances have been ...