Ara
Toplam kayıt 7, listelenen: 1-7
Neonatal neurodegeneration in alzheimer's disease transgenic mouse model
(IOS Press, 2018)
Alzheimer's disease (AD) is a progressive disorder characterized by a variety of molecular pathologies causing cortical dementia with a prominent memory deficit. Formation of the pathology, which begins decades before the ...
Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival
(Nature Publishing Group, 2019)
The circadian rhythm is driven by a master clock within the suprachiasmatic nucleus which regulates the rhythmic secretion of melatonin. Bmal1 coordinates the rhythmic expression of transcriptome and regulates biological ...
Expression of Pea3 protein subfamily members in hippocampus and potential regulation following neuronal stimulation
(Elsevier Ireland Ltd, 2020)
Pea3 proteins belong to a subfamily of the E-twentysix (ETS) domain superfamily of transcription factors, which play various roles during development. Polyoma Enhancer-Activator 3 (Pea3) proteins Pea3, ERM and Er81 are ...
Neuroprotective effects of curcumin-loaded emulsomes in a laser axotomy-induced CNS injury model
(Dove Medical Press Ltd, 2020)
Purpose: Curcumin, a polyphenol isolated from the rhizomes of turmeric, holds great potential as a neuroprotective agent in addition to its anti-inflammatory and antioxidant characteristics. The poor bioavailability and ...
Beyond the therapeutic effect of RTMS in Alzheimer’s disease: A possible neuroprotective role of hippocampal BDNF?: A minireview
(Bentham Science Publishers B.V., 2018)
Repetitive transcranial magnetic stimulation (rTMS) is a well known non-invasive brain stimulation procedure which is capable of inducing the expression of the hippocampal BDNF that has been already shown to exert significant ...
Effects of cichorium intybus on GABA(A) receptors and apoptosis in pentylenetetrazole-induced kindling in rats
(Kare Publishing, 2021)
Objectives: This study was designed to determine the effects of Cichorium intybus (CI) on apoptosis and GABA(A) receptor density in the brains of rats in pentyleneterazole induced kindling.
Methods: The rats were divided ...
Dual action of exosomes derived from in vitro A beta toxicity model: The role of age for pathological response
(Elsevier Ireland Ltd, 2023)
Exosomes released from different cell types of the central nervous system play an essential role in the patho-genesis of Alzheimer's disease (AD). In this study, we aimed to create an animal model by injecting exosomes ...