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In silico analysis of a highly mutated gene in cancer provides insight into abnormal mRNA splicing: Splicing factor 3B subunit 1k700e mutant
(MDPI AG, 2020)
Cancer is the second leading cause of death worldwide. The etiology of the disease has remained elusive, but mutations causing aberrant RNA splicing have been considered one of the significant factors in various cancer ...
Understanding the differential selectivity of arrestins toward the phosphorylation state of the receptor
(American Chemical Society, 2016)
Proteins in the arrestin family exhibit a conserved structural fold that nevertheless allows for significant differences in their selectivity for G-protein coupled receptors (GPCRs) and their phosphorylation states. To ...