Bölüm "İstanbul Medipol Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümü" Makale Koleksiyonu için listeleme
Toplam kayıt 2, listelenen: 1-2
-
Catalytically competent non-transforming H-RASG12P mutant provides insight into molecular switch function and GAP-independent GTPase activity of RAS
(Nature Publishing Group, 2019)RAS mutants have been extensively studied as they are associated with development of cancer; however, H-RASG12P mutant has remained untouched since it does not lead to transformation in the cell. To the best of our knowledge, ... -
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ...