Başlık için Makale Koleksiyonu listeleme
Toplam kayıt 81, listelenen: 27-46
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Exploring the prognostic significance of set-domain containing 2 (setd2) expression in advanced and castrate-resistant prostate cancer
(2024)SET-domain containing 2 (SETD2) is a histone methyltransferase and an epigenetic modifier with oncogenic functionality. In the current study, we investigated the potential prognostic role of SETD2 in prostate cancer. A ... -
FbpA iron storage and release are governed by periplasmic microenvironments
(Royal Society of Chemistry, 2017)Ferric binding protein (FbpA) is part of an elaborate iron piracy mechanism evolved in Gram-negative bacteria, shuttling iron in the periplasmic space, from the outer to the cytoplasmic membrane side. We address how the ... -
Flexible beacon design for 60 GHz wireless personal area networks
(2019)In this paper we investigate the effect of different beaconing strategies for wireless personal area networks. Beacons are used by network coordinators to indicate the existence of the networks. A long beacon range protects ... -
Fuzzy classification methods based diagnosis of Parkinson’s disease from speech test cases
(Bentham Science Publishers, 2019)Background: Together with the Alzheimer’s disease, Parkinson’s disease is considered as one of the two serious known neurodegenerative diseases. Physicians find it hard to predict whether a given patient has already developed ... -
Genomic biomarker discovery in disease progression and therapy response in bladder cancer utilizing machine learning
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Cancer in all its forms of expression is a major cause of death. To identify the genomic reason behind cancer, discovery of biomarkers is needed. In this paper, genomic data of bladder cancer are examined for the purpose ... -
Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus
(Nature Publishing Group, 2016)Wild populations of the house mouse (Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology. We provide whole genome ... -
A GIPC1-palmitate switch modulates dopamine drd3 receptor trafficking and signaling
(Amer Soc Microbiology, 2016)Palmitoylation is involved in several neuropsychiatric and movement disorders for which a dysfunctional signaling of the dopamine D3 receptor (Drd3) is hypothesized. Computational modeling of Drd3's homologue, Drd2, has ... -
Glacial lakes mapping using multi satellite PlanetScope imagery and deep learning
(MDPI AG, 2020)Glacial lakes mapping using satellite remote sensing data are important for studying the effects of climate change as well as for the mitigation and risk assessment of a Glacial Lake Outburst Flood (GLOF). The 3U cubesat ... -
HM-net: A regression network for object center detection and tracking on wide area motion imagery
(IEEE-Institute of Electrical and Electronics Engineers Inc., 2022)Wide Area Motion Imagery (WAMI) yields high resolution images with a large number of extremely small objects. Target objects have large spatial displacements throughout consecutive frames. This nature of WAMI images makes ... -
Human action recognition approaches with video datasets-A survey
(Elsevier B.V., 2021)Human Activity Recognition has recently attracted considerable attention. This has been triggered by the rapid development of advance technologies and learning methods. Human action recognition can be actively used in a ... -
Human behavior modeling for simulating evacuation of buildings during emergencies
(Elsevier, 2019)Every year, a considerably large number of disasters occur as a result of natural events or human faults. In order to decrease the damage and casualties associated with each disaster, it is crucial to get prepared for these ... -
A hybrid deep model using deep learning and dense optical flow approaches for human activity recognition
(IEEE - Institute of Electrical and Electronics Engineers, Inc., 2020)Human activity recognition is a challenging problem with many applications including visual surveillance, human-computer interactions, autonomous driving and entertainment. In this study, we propose a hybrid deep model to ... -
Identifying side effects of commonly used drugs in the treatment of Covid 19
(Nature Research, 2020)To increase the success in Covid 19 treatment, many drug suggestions are presented, and some clinical studies are shared in the literature. There have been some attempts to use some of these drugs in combination. However, ... -
IEEE 802.15.7r1 reference channel models for visible light communications
(IEEE-Inst Electrical Electronics Engineers Inc, 2017)The IEEE has established the standardization group 802.15.7r1 "Short Range Optical Wireless Communications", which is currently in the process of developing a standard for visible light communication (VLC). As with any ... -
Imaging of the axon initial segment
(Blackwell Publishing, Inc., 2019)The axon initial segment (AIS) is the first 20- to 60-μm segment of the axon proximal to the soma of a neuron. This highly specialized subcellular domain is the initiation site of the action potential and contains a high ... -
An improved demand forecasting model using deep learning approach and proposed decision integration strategy for supply chain
(Wiley-Hindawi, 2019)Demand forecasting is one of the main issues of supply chains. It aimed to optimize stocks, reduce costs, and increase sales, profit, and customer loyalty. For this purpose, historical data can be analyzed to improve demand ... -
In silico analysis of a highly mutated gene in cancer provides insight into abnormal mRNA splicing: Splicing factor 3B subunit 1k700e mutant
(MDPI AG, 2020)Cancer is the second leading cause of death worldwide. The etiology of the disease has remained elusive, but mutations causing aberrant RNA splicing have been considered one of the significant factors in various cancer ... -
Inhibition of AKT signaling alters beta IV spectrin distribution at the AIS and increases neuronal excitability
(Frontiers Media S.A., 2021)The axon initial segment (AIS) is a highly regulated subcellular domain required for neuronal firing. Changes in the AIS protein composition and distribution are a form of structural plasticity, which powerfully regulates ... -
Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS
(NLM (Medline), 2022)Undruggability of RAS proteins has necessitated alternative strategies for the development of effective inhibitors. In this respect, phosphorylation has recently come into prominence as this reversible post-translational ... -
Inhibition of SARS-CoV-2 main protease: A repurposing study that targets the dimer interface of the protein
(Taylor and Francis Ltd., 2022)Coronavirus disease-2019 (COVID-19) was firstly reported in Wuhan, China, towards the end of 2019, and emerged as a pandemic. The spread and lethality rates of the COVID-19 have ignited studies that focus on the development ...