WoS Q Kategorisi "Q3" Diğer Yayınlar Koleksiyonu İçin Listeleme
Toplam kayıt 3, listelenen: 1-3
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Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ... -
Modulation of protein-protein interactions for the development of effective therapeutics - from a joint perspective of experiment and computation
(Bentham Science Publishers B.V., 2018)Many proteins present in living organisms act as obligate oligomers – that is to say - they require other protein partners to function properly. Oligomerization does not only lead to the formation of physical interactions, ... -
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
(Bentham Science Publishers Ltd, 2018)Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ...