Scopus Q Kategorisi "Q1" Diğer Yayınlar Koleksiyonu İçin Listeleme
Toplam kayıt 6, listelenen: 1-6
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Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ... -
Glaucoma detection using image processing techniques: A literature review
(Elsevier, 2019)The term glaucoma refers to a group of heterogeneous diseases that cause the degeneration of retinal ganglion cells (RGCs). The degeneration of RGCs leads to two main issues: (i) structural changes to the optic nerve head ... -
Modulation of protein-protein interactions for the development of effective therapeutics - from a joint perspective of experiment and computation
(Bentham Science Publishers B.V., 2018)Many proteins present in living organisms act as obligate oligomers – that is to say - they require other protein partners to function properly. Oligomerization does not only lead to the formation of physical interactions, ... -
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
(Bentham Science Publishers Ltd, 2018)Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ... -
A review of computational drug repositioning: Strategies, approaches, opportunities, challenges, and directions
(BMC, 2020)Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an important role in optimizing the ... -
Utilization of biased G protein-coupled receptor signaling towards development of safer and personalized therapeutics
(MDPI, 2019)G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family. Discovery of beta-arrestin ...