Bölüm "İstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü" Makale Koleksiyonu için listeleme
Toplam kayıt 14, listelenen: 1-14
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A 3-DoF robotic platform for the rehabilitation and assessment of reaction time and balance skills of MS patients
(Public Library of Science, 2023)The central nervous system (CNS) exploits anticipatory (APAs) and compensatory (CPAs) postural adjustments to maintain the balance. The postural adjustments comprising stability of the center of mass (CoM) and the pressure ... -
Antileishmanial activity of BNIPdaoct- and BNIPdanon-loaded emulsomes on leishmania infantum parasites
(Frontiers Media S.A., 2022)Among bisnaphthalimidopropyl (BNIP) derivatives, BNIPDaoct and BNIPDanon recently came forward with antileishmanial activities beyond the standard, commercialized antileishmanial therapies. However, high-level toxicity on ... -
A behavioral paradigm for cortical control of a robotic actuator by freely moving rats in a one-dimensional two-target reaching task
(Elsevier B.V., 2022)Background: Controlling the trajectory of a neuroprosthesis to reach distant targets is a commonly used brain-machine interface (BMI) task in primates and has not been available for rodents yet. New method: Here, we describe ... -
Bioconjugated beta-cyclodextrin-perfluorohexane nanocone clusters as functional nanoparticles for nanoparticle-mediated histotripsy
(American Chemical Society, 2022)Nanocone clusters (NCCs) are new-generation agents of nanoparticle-mediated histotripsy (NMH) recently developed to address the limitations of previously designed nanodroplets (NDs). NCCs can be obtained by simply mixing ... -
Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a
(American Chemical Society, 2022)Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ... -
Delivery of curcumin within emulsome nanoparticles enhances the anti-cancer activity in androgen-dependent prostate cancer cell
(Springer, 2023)Background: Curcumin, a dietary polyphenol isolated from turmeric, is a potent phytochemical possessing intrinsic anticancer activities against various cancer types including prostate cancer. However, low water solubility ... -
Experimental and computational investigation of clustering behavior of cyclodextrin-perfluorocarbon inclusion complexes as effective histotripsy agents
(American Chemical Society, 2022)Recently developed nanocones (NCs), which are inclusion complexes that are made up of cyclodextrins (CDs) and perfluorocarbons (PFCs), have shown promising results in nanoparticle-mediated histotripsy (NMH) applications ... -
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ... -
Microwave-promoted continuous flow systems in nanoparticle synthesis-A perspective
(American Chemical Society, 2021)Microwave-promoted continuous flow systems have emerged as a game-changer in nanoparticle synthesis. Owing to the excellent compatibility between fast, sustainable microwave heating and one-step, efficient flow chemistry, ... -
Neuroprotective effects of curcumin-loaded emulsomes in a laser axotomy-induced CNS injury model
(Dove Medical Press Ltd, 2020)Purpose: Curcumin, a polyphenol isolated from the rhizomes of turmeric, holds great potential as a neuroprotective agent in addition to its anti-inflammatory and antioxidant characteristics. The poor bioavailability and ... -
A new strategy for direct solution electrospinning of phosphorylated poly(vinyl chloride)/polyethyleneimine blend in alcohol media
(Elsevier Ltd, 2023)Phosphorylated poly(vinyl chloride) (PPVC)/polyethyleneimine (PEI)-based nanofibers were produced via electrospinning in their blended solutions for the first time. For this purpose, PVC was partially converted into PVC-N3 ... -
Oxide glass formers extending persistent luminescence in Eu and Dy co-doped strontium aluminates
(Elsevier B.V., 2023)Recent work has shown that the incorporation of electrically charged, non-bridging oxygen (NBO) species into Eu and Dy co-doped Sr4Al14O25 (S4A7ED) crystal structure, in the form of BØ2O−, induces the clustering of divalent ... -
SELEX against whole-cell bacteria resulted in lipopolysaccharide binding aptamers
(Elsevier B.V., 2022)Nucleic acid aptamers are target-specific oligonucleotides selected from combinatorial libraries through an iterative in vitro screening process known as Systemic Evolution of Ligands by Exponential Enrichment (SELEX). In ... -
Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab
(MDPI, 2022)The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ...