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Assessment of aprotinin loaded microemulsion formulations for parenteral drug delivery: Preparation, characterization, in vitro release and cytotoxicity studies
(Bentham Science, 2016)The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics and release behaviour of different Technetium-99m (Tc-99m)-Aprotinin ... -
Assessment of job satisfaction, work-related strain, and perceived stress in nurses working in different departments in the same hospital: A survey study
(Springer, 2020)ObjectiveWe aimed to evaluate whether working at ICU, inpatient services, or the operating room creates differences in job satisfaction (JS), work-related strain (WRS), and perceived stress (PS) of nurses.Research ... -
The association of oxidative stress and DNA damage with XRCC1 and XRCC3 polymorphisms in radiology technicians
(SAGE Publications Ltd, 2022)Ionizing radiation has widespread use in medicine in the diagnosis and treatment of many medical conditions. Radiology technicians are one group that is occupationally exposed to low doses of radiation. There are questions ... -
Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: Formulation, characterization, in vitro-ex vivo evaluation
(Taylor & Francis Ltd, 2022)In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris. Physicochemical properties such as viscosity, pH and mechanical properties were evaluated. ... -
Benzotriazole-oxadiazole hybrid compounds: Synthesis, anticancer activity, molecular docking and ADME profiling studies
(Elsevier B.V., 2022)Herein the designed novel benzotriazole-oxadiazole hybrid compounds were synthesized using both conventional method and ultrasound sonication (US) as an environmentally friendly method. It was observed that the US method ... -
Binary synergistic combinations of lavender and fennel essential oils with amoxicillin
(Georg Thieme Verlag, 2023)Microbial resistance is an important problem in modern healthcare systems. In addition to drug resistance, the side effects of current antibiotic applications are also known issues. In this present study, binary combinations ... -
Bioautography for evaluation of several Lavandula L. and origanum species antimicrobial and antioxidant activity
(Istanbul Medipol University, 2023)In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal ... -
Biocompatibility of biomimetic multilayered alginate-chitosan/beta-TCP scaffold for osteochondral tissue
(Elsevier Science, 2015)Biomimetic three-layered monolithic scaffold (TLS) intended for treatment of osteochondral defects was fabricated by using freeze drying method. The multilayered material was prepared with chitosan (C) and alginate (A) ... -
Biological activities of the fruit essential oil, fruit, and root extracts of ferula drudeana korovin, the putative anatolian ecotype of the silphion plant
(MDPI, 2023)In the present study, preliminary phytochemical investigations were performed on the fruit essential oil and antioxidant-rich methanolic extracts of the fruits and roots of Ferula drudeana, the putative Anatolian ecotype ... -
Biological activities of the natural coumarins from apiaceae plants
(ACG Publications, 2023)Nineteen natural coumarins; badrakemin (1), colladonin (2), 14'-acetoxybadrakemin (3), anatolicin (4), 14'-hydroxycolladonin (5), badrakemone (6), karatavicinol (7), 14'-acetoxybadrakemone (8), 14'-acetoxycolladonin (9), ... -
Biological activities of the Ornithogalum orthophyllum and its in silico ADMET profile
(TMR Publishing Group, 2021)Background: The bulbs and aerial parts of Ornithogalum are used in Turkey both as food and to treat various ailments, and some of its medical applications are well known. However, the biological activities of Ornithogalum ... -
Biological activity and chemical composition of the essential oil from the fruits of Ferula halophila Peşmen
(Istanbul Medipol University, 2023)The hydrodistilled essential oils of the dried fruits of F. halophila Peşmen, an endemic species growing near Salt Lake in Central Anatolia, were analyzed by GC and GC-MS systems; 27 and 24 compounds representing 92.1% and ... -
Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.
(Istanbul Medipol University, 2023)The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were ... -
Biological properties and HPLC analyses of four medicinal plants extracts obtained at different extraction temperatures
(Wiley, 2022)In the present study, extracts of four medicinal plants (Cajanus cajan, Carica papaya, Morinda morindoides, and Senna alexandrina) obtained at two different extraction temperatures (24 and 45 degrees C) were investigated ... -
Butyrylcholinesterase-inhibiting natural coumarin molecules as potential leads
(Elsevier Ltd, 2021)Seventeen natural coumarin derivatives; badrakemin (1), 14′-acetoxybadrakemin (2), badrakemone (3), 14′-acetoxybadrakemone (4), colladonin (5), colladonin acetate (6), 14′-acetoxycolladonin (7), karatavicinol (8), deltoin ... -
Characterization of Opuntia ficus-indica (L.) Mill. fruit volatiles and antibacterial evaluation
(Badebio Biotechnololgy Ltd, 2018)Opuntia ficus-indica (L.) Mill. fruits known as prickly pear cactus are used in folk medicine as well as food. In the present study it was aimed to extract the volatile constituents of O. ficus-indica fruits by n-hexane. ... -
Chemical characterization and multidirectional biological effects of different solvent extracts of arum elongatum: in vitro and in silico approaches
(Wiley-VCH Verlag, 2023)Arum elongatum (Araceae) is widely used traditionally for the treatment of abdominal pain, arterial hypertension, diabetes mellitus, rheumatism and hemorrhoids. This study investigated the antioxidant properties, individual ... -
Chemical characterization of Glaucosciadium cordifolium (Boiss.) B. L. Burtt & P. H. Davis essential oils and their antimicrobial, and antioxidant activities
(Istanbul University, 2019)Chemical composition of volatile oils obtained from the roots, fruits and aerial parts of Glaucosciadium cordifolium (Boiss.) B. L. Burtt& P. H. Davis (Apiaceae) were analyzed using gas chromatography-flame ionization ... -
Chemical composition and in vitro mutagenic, antioxidant and anti-inflammatory activities of Lavandula angustifolia Mill. essential oil from Turkey
(Marmara University, 2022)The essential oil obtained from Lavandula angustifolia Mill. (Lavander) has many pharmacological effects, including antioxidant, antifungal, antibacterial and carminative effects. Lavandula angustifolia essential oil (LEO) ... -
Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils
(Consejo Superior de Investigaciones Científicas (CSIC), 2021)The chemical compositions of the essential oils (EOs) obtained by hydrodistillation from different parts of Cnidium silaifolium ssp. orientale (Boiss.) Tutin were analyzed both by GC-FID and GC/MS, simultaneously. One ...
