Başlık için Makale Koleksiyonu listeleme
Toplam kayıt 280, listelenen: 157-176
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Investigation of genotoxicity risk and DNA repair capacity in breast cancer patients using anastrozole
(Kare Publishing, 2018)OBJECTIVE: Breast cancer is the most common cancer in women worldwide and the incidence increases in postmenopausal women. Anastrozole is a non-steroidal (type II), third-generation aromatase inhibitor (AI) that is used ... -
Investigation of hidden crisis of prescription drug abuse in Turkey: Pregabalin monitoring
(Istanbul Medipol University, 2022)This is a cross-sectional retrospective observational national study. Abuse/misuse of the pregabalin and related parameters analyzed. Pregabalin was mostly pre-scribed by general practitioners (26.2%). Pregabalin prescribing ... -
Investigation of the deoxynivalenol and ochratoxin a levels by high-performance liquid chromatography of cereals sold in the markets in Türkiye
(Sociedade Brasileira de Ciencia e Tecnologia de Alimentos, SBCTA, 2023)The current research was conducted to determine the deoxynivalenol (DON) and ochratoxin A (OTA) levels of 24 pieces of wheat flour, 24 pieces of rice, 24 pieces of corn flour, and 24 pieces of whole wheat flour obtained ... -
Investigation of the diabetic patients’ knowledge on diabetes and the role of clinical pharmacist in providing pharmaceutical care to them
(İstanbul Medipol University, 2020)Type 2 Diabetes is a common incurable metabolic disorder with worldwide increasing prevalence. International Diabetic Association noticed that there is a very fast and alarming increase in the worldwide prevalence of ... -
Investigation of therapeutic effects in the wound healing of chitosan/pGM-CSF complexes
(Universidade de São Paulo, 2022)Granulocyte macrophage colony-stimulating factor (GM-CSF) has been shown to promote the growth, proliferation, and migration of endothelial and keratinocyte cells. Chitosan has been widely used as a biopolymer in wound-healing ... -
Is ChatGPT reliable and accurate in answering pharmacotherapy-related inquiries in both Turkish and English?
(2024)Introduction: Artificial intelligence (AI), particularly ChatGPT, is becoming more and more prevalent in the healthcare field for tasks such as disease diagnosis and medical record analysis. The objective of this study is ... -
Is it safe to reuse dental implant healing abutments sterilized and serviced by dealers of dental implant manufacturers? An in vitro sterility analysis
(Lippincott Williams and Wilkins, 2015)Purpose: This study was undertaken to investigate the sterility of used healing abutments sterilized and serviced by dealers of dental implant manufacturers. Materials and Methods: Sixty used but sterilized healing abutments ... -
Laurocerasus officinalis Roem. fruit extract induces cell death through caspase mediated apoptosis in gastric cancer cell lines
(Walter de Gruyter GmbH, 2021)Objectives: Laurocerasus officinalis Roem. fruits are traditionally used for several health problems. Although there are some studies about its antiproliferative effects on different cancer cells, no study was reported ... -
Matrin ve oksimatrinin mikrobiyal transformasyonu ve metabolitlerinin in vitro biyolojik aktivitelerinin incelenmesi
(Mersin Üniversitesi, 2020)Amaç: Matrin ve oksimatrin bileşiklerinin mikrobiyal transformasyon yolu ile metabolitlerin karşılaştırmalı olarak biyolojik aktivitelerinin incelenmesi hedeflenmiştir. Yöntem:30 farklı mikroorganizmanın sıvı besiyerinde ... -
Melatonin ameliorates oxidative DNA damage and protects against formaldehyde-induced oxidative stress in rats
(E-Century Publishing Corp, 2017)Formaldehyde (FA) is an organic chemical which is widely used all over the world and has hazardous effects for the environment. FA can react with many biomolecules in the biological systems and lead to toxic effects on ... -
Microwave supported synthesis of some novel 1,3-Diarylpyrazino[1,2-a] benzimidazole derivatives and investigation of their anticancer activities
(Elsevier, 2011)The syntheses of 1,3-diarylpyrazino[1,2-a]benzimidazole derivatives and the investigation of their anticancer activities were studied. For this, 2-aryloylbenzimidazole derivatives were reacted with 2-bromoacetophenones in ... -
Miyokardiyal iskemi sonrası gelişen akut böbrek hasarı üzerine Nebivolol’ün etkisi: Preklinik bir çalışma
(Galenos Yayıncılık, 2018)Amaç: Akut miyokard iskemisinin reperfüzyonu (IR) sırasında miyokard dokusunun yanı sıra diğer dokularda da hasarın söz konusu olduğu gösterilmiştir. Böbrek hasarı bunlardan birisidir. Altta yatan mekanizmalara yönelik pek ... -
Molecular modelling and activity analysis of mycobacterium tuberculosis DNA gyrase B ATPase active site
(University of Istanbul, 2017)Computer-based algorithms and statistical techniques such as receiver operating characteristic (ROC) curves are increasingly used for the design of new ligands. X-ray crystallographic data and homology models allow examining ... -
Molecular modelling and compound activity of the escherichia coli and staphylococcus aureus DNA gyrase B ATPase site
(University of Istanbul, 2017)Development of new treatment ligands that can distinguish Escherichia coli (E. coli) from Staphylococcus aureus (S. aureus) is important because of bacterium multiple drug resistance. High-throughput virtual screening ... -
Morphological and biochemical investigation of the protective effects of panax ginseng on methotrexate-induced testicular damage
(Istanbul University Press, 2023)Objective: Methotrexate (MTX) is a chemotherapeutic agent that causes testicular toxicity used in the cure of various types of cancer. The anti-oxidant and anti-cancer effects of Panax ginseng (PxG) have been reported in ... -
Multiple online-HPLC methodologies and biological properties of leaves and stem barks extracts of Chrysanthellum indicum
(Elsevier Inc., 2024)Chrysanthellum indicum, an annual herb with yellow flowers, is used as a functional food in Asia and Africa for health purposes. In this study, we thoroughly investigated the characterization of phytochemicals within C. ... -
Nafion/aquivion-based composite lithium ion exchange membranes for high capacity Li-S batteries
(Wiley-VCH Verlag GmbH, 2022)Lithiated Nafion (Li-Naf) and lithiated Aquivion (Li-Aqu) ion exchange membranes are applied as electrolyte and separator to prevent the polysulfide shuttle effect in Li−S batteries. The production and characterization of ... -
Nanofibrous wound dressing material by electrospinning method
(Taylor & Francis As, 2019)Wound dressings are very useful materials for accelerating the wound healing process. In this study, nanofibrous wound dressings were produced from blending solution of Poly-lactic acid(PLA)/Chitosan(C)/Starch(S)/Zinc ... -
Nanofiller-based novel hybrid composite membranes for high-capacity lithium-sulfur batteries
(John Wiley and Sons Inc, 2023)Herein, Al2O3 nanofiller-reinforced lithiated Nafion:Aquivion hybrid composite ion-exchange membranes have been produced by mixing lithiated Nafion and Aquivion ionomers. After the electrochemical tests, the Li-Naf : ... -
Neopapillarine, an unusual coumarino-alkaloid from the root extract of neocryptodiscus papillaris with cytotoxic activity on renal cancer cells
(MDPI, 2020)Several simple and prenylated coumarin derivatives were isolated from the dichloromethane extract of the root of Neocryptodiscus papillaris based on moderate cytotoxic activity of the extract in COLO205, KM12 and MCF7 ...
