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The impact of metabolic syndrome on increased risk of thyroid nodules and size
(Sage Publications Inc, 2018)Aim: The present research aimed to determine the relation between metabolic syndrome (MetS) and thyroid volume and nodule prevalence among Turkish population patients. Methods: This retrospective cohort study was carried ... -
Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism
(American Society for Clinical Investigation Inc, 2018)Defects in genes mediating thyroid hormone biosynthesis result in dyshormonogenic congenital hypothyroidism (CH). Here, we report homozygous truncating mutations in SLC26A7 in 6 unrelated families with goitrous CH and show ... -
Confocal laser endomicroscopy and optical coherence tomography for the diagnosis of prostate cancer: A needle-based, in vivo feasibility study protocol (Ideal phase 2a)
(JMIR Publications, Inc, 2018)Background: Focal therapy for prostate cancer has been proposed as an alternative treatment to whole-gland therapies in selected men to diminish side effects in localized prostate cancer. As nowadays imaging cannot offer ... -
Mülteci ve yerleşik ergenlerde depresyona yatkınlık ve algılanan sosyal destek düzeyleri
(2018)Amaç: Bu çalışma, İstanbul ili Bağcılar ilçesindeki ortaokul ve liselerde okuyan yerleşik ve mülteci öğrencilerin depresyona yatkınlığının belirlenmesi ve algılanan sosyal destek düzeylerinin karşılaştırılması amacıyla ... -
Low vitamin D deficiency associated with thyroid disease among type 2 diabetic mellitus patients
(Elmer Press, 2018)Background: The aim of this study was to investigate the relationship between vitamin D deficiency and thyroid diseases among type 2 diabetes mellitus (T2DM) patients.Methods: This was a cohort case and control study, 546 ... -
Neonatal neurodegeneration in alzheimer's disease transgenic mouse model
(IOS Press, 2018)Alzheimer's disease (AD) is a progressive disorder characterized by a variety of molecular pathologies causing cortical dementia with a prominent memory deficit. Formation of the pathology, which begins decades before the ... -
Experimentally induced metamorphosis in highly regenerative axolotl (ambystoma mexicanum) under constant diet restructures microbiota
(Nature Publishing Group, 2018)Axolotl (Ambystoma mexicanum) is a critically endangered salamander species and a model organism for regenerative and developmental biology. Despite life-long neoteny in nature and in captive-bred colonies, metamorphosis ... -
Als2 silencing affects the expression of two NF-κB targeted genes via uxt in adult mouse primary spinal motor neuron culture
(Logos Medical Publishing, 2018)Aim: Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder affecting motor neurons. Als2 is one of the genes that cause ALS, and its mutations leads to loss of function in alsin protein. The interaction between ... -
Transfer and integration of breast milk stem cells to the brain of suckling pups
(Nature Publishing Group, 2018)Beside its unique nutritional content breast milk also contains live cells from the mother. Fate of these cells in the offspring has not been adequately described. In this study, we aimed to detect and identify maternal ... -
The significance of neutrophil-to-lymphocyte ratio in idiopathic epiretinal membrane
(Springer, 2018)To assess the levels of neutrophil-to-lymphocyte ratio (NLR) in patients with idiopathic epiretinal membrane (iERM) and to compare the NLR results of patients with iERM and healthy controls. This retrospective study enrolled ... -
The impact of vitamin D deficiency on retinopathy and hearing loss among type 2 diabetic patients
(Hindawi Limited, 2018)Aim. The current study was aiming to investigate the relation between vitamin D, retinopathy, and hearing loss among type 2 diabetes mellitus (T2DM) patients. Methods. Cross-sectional study carried on 638 subjects aged ... -
A clinical evaluation of the new digital single-use flexible ureteroscope (UscopePU3022): An international prospective multicentered study
(Polish Urological Association, 2018)Introduction We assessed the clinical performance of a new digital single-use flexible ureteroscope (UscopePU3022). Material and methods A prospective cohort study was carried out across 11 centers (July-Oct. 2017). The ... -
The value of microscopic-observation drug susceptibility assay in the diagnosis of tuberculosis and detection of multidrug resistance
(Blackwell Munksgaard, 2018)Inexpensive, rapid, and reliable tests for detecting the presence and drug susceptibility of Mycobacterium tuberculosis complex (MTBC) are urgently needed to control the transmission of tuberculosis. In this study, we aimed ... -
Camel's milk allergy
(Ocean Side Publications Inc., 2018)Introduction: Camel's milk is a safe and therapeutic nutrient. Camel's milk allergy is almost unknown. Objective: To identify the clinical and laboratory features of camel's milk allergy. Methods: In this retrospective ... -
N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions
(Taylor & Francis Ltd., 2018)Objective: To investigate the molecular mechanisms of colistimethate sodium-induced nephrotoxicity and the protective effect of N-acetylcysteine (NAC) against nephrotoxicity.Methods: Twenty-eight Wistar rats were divided ... -
Impact on genitourinary function and quality of life following focal irreversible electroporation of different prostate segments
(AVES, 2018)PURPOSE We aimed to evaluate the genitourinary function and quality of life (QoL) following the ablation of different prostate segments with irreversible electroporation (IRE) for localized prostate cancer (PCa). METHODS ... -
Verteporfin mediated sequence dependent combination therapy against ovarian cancer cell line
(Elsevier Science Sa, 2018)Ovarian Cancer is one of the deadliest gynecological cancer showing high resistance to chemotherapy. Non overlapping and synergistic combination therapies are the best option to overcome this multi-pathological silent ... -
A retrospective analysis of anaerobic bacteria isolated in 236 cases of pleural empyema and their prevalance of antimicrobial resistance in Turkey
(Clinical Laboratory Publ, 2018)Background: Parapneumonic effusions usually occur secondary to an infection and produce pus (empyema) that accumulates in the pleural space. We aimed to evaluate the prevalence of anerobes in patients with empyema and to ... -
The neuroprotective effects of hypothermia on bilirubin-ınduced neurotoxicity in vitro
(Karger, 2018)Background: In high-risk newborns indirect hyperbilirubinennia can lead to acute bilirubin encephalopathy and kernicterus. Despite the current therapeutic modalities, preventing or reversing the neurotoxicity cannot be ... -
Needle-based optical coherence tomography for the detection of prostate cancer: A visual and quantitative analysis in 20 patients
(Spie-Soc Photo-Optical Instrumentation Engineers, 2018)Diagnostic accuracy of needle-based optical coherence tomography (OCT) for prostate cancer detection by visual and quantitative analysis is defined. 106 three-dimensional (3-D)-OCT data sets were acquired in 20 prostates ...