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dc.contributor.authorYılmaz, İlhan
dc.contributor.authorEşeoğlu, Metehan
dc.contributor.authorÖnen, Mehmet Reşid
dc.contributor.authorTanrıverdi, Osman
dc.contributor.authorKılıç, Mustafa
dc.contributor.authorYılmaz, Adem
dc.contributor.authorMüslüman, Ahmet Murat
dc.contributor.authorAydın, Mehmet Dumlu
dc.contributor.authorGündoğdu, Cemal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:04:42Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:04:42Z
dc.date.issued2017en_US
dc.identifier.citationYılmaz, İ., Eşeoğlu, M., Önen, M. R., Tanrıverdi, O., Kılıç, M., Yılmaz, A. ... Gündoğdu, C. (2017). Inverse association between basilar artery volume and neuron density in the stellate ganglion following bilateral common carotid artery ligation: An experimental study. World Neurosurgery, 100, 138-143. https://dx.doi.org/10.1016/j.wneu.2016.12.034en_US
dc.identifier.issn1878-8750
dc.identifier.issn1878-8769
dc.identifier.urihttps://dx.doi.org/10.1016/j.wneu.2016.12.034
dc.identifier.urihttps://hdl.handle.net/20.500.12511/4094
dc.descriptionWOS: 000401930000017en_US
dc.descriptionPubMed ID: 28007603en_US
dc.description.abstractOBJECTIVE: This study examined the relationship between neuron density in the stellate ganglion and the severity of basilar artery (BA) enlargement after bilateral common carotid artery ligation. METHODS: Rabbits (n = 24) were randomly divided into 3 groups: unoperated control group (n = 4), experimental group subjected to bilateral common carotid artery ligation (n [ 15), and sham-operated control group (n = 5). Histologic examination of the BAs and stellate ganglia was performed 2 months later. Permanent bilateral common carotid artery ligation was induced by ligation of common carotid arteries at prebifurcation levels as a model for steno-occlusive carotid artery disease. RESULTS: Mean BA volume and neuron density in stellate ganglia for all animals were 4200 mu m(3) +/- 240 and 8325 mu m(3) +/- 210. In sham- operated animals, the mean values were 4360 mu m(3) +/- 340 and 8250 mm(3) +/- 250. For the experimental group, mean volume and density in animals with slight dilatation of the BA (n = 6) were 4948 mu m(3) +/- 680 and 10,321 mm(3) +/- 120, whereas in animals with severe dilatation (n = 9), the values were 6728 mu m(3) +/- 440 and 6300 mm(3) +/- 730. An inverse association was observed between degree of BA enlargement and stellate ganglia neuronal density. CONCLUSIONS: High neuron density in stellate ganglia may protect against steno-occlusive carotid artery disease by preventing BA dilatation and aneurysm formation in the posterior circulatory arteries.en_US
dc.language.isoengen_US
dc.publisherElsevier Science Incen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectBasilar Arteryen_US
dc.subjectBilateral Common Carotid Artery Ligationen_US
dc.subjectNeuron Density in Stellate Ganglionen_US
dc.titleInverse association between basilar artery volume and neuron density in the stellate ganglion following bilateral common carotid artery ligation: An experimental studyen_US
dc.typearticleen_US
dc.relation.journalWorld Neurosurgeryen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalıen_US
dc.identifier.volume100en_US
dc.identifier.startpage138en_US
dc.identifier.endpage143en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.wneu.2016.12.034en_US


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