dc.contributor.author | Yılmaz, İlhan | |
dc.contributor.author | Eşeoğlu, Metehan | |
dc.contributor.author | Önen, Mehmet Reşid | |
dc.contributor.author | Tanrıverdi, Osman | |
dc.contributor.author | Kılıç, Mustafa | |
dc.contributor.author | Yılmaz, Adem | |
dc.contributor.author | Müslüman, Ahmet Murat | |
dc.contributor.author | Aydın, Mehmet Dumlu | |
dc.contributor.author | Gündoğdu, Cemal | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:04:42Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:04:42Z | |
dc.date.issued | 2017 | en_US |
dc.identifier.citation | Yılmaz, İ., Eşeoğlu, M., Önen, M. R., Tanrıverdi, O., Kılıç, M., Yılmaz, A. ... Gündoğdu, C. (2017). Inverse association between basilar artery volume and neuron density in the stellate ganglion following bilateral common carotid artery ligation: An experimental study. World Neurosurgery, 100, 138-143. https://dx.doi.org/10.1016/j.wneu.2016.12.034 | en_US |
dc.identifier.issn | 1878-8750 | |
dc.identifier.issn | 1878-8769 | |
dc.identifier.uri | https://dx.doi.org/10.1016/j.wneu.2016.12.034 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/4094 | |
dc.description | WOS: 000401930000017 | en_US |
dc.description | PubMed ID: 28007603 | en_US |
dc.description.abstract | OBJECTIVE: This study examined the relationship between neuron density in the stellate ganglion and the severity of basilar artery (BA) enlargement after bilateral common carotid artery ligation. METHODS: Rabbits (n = 24) were randomly divided into 3 groups: unoperated control group (n = 4), experimental group subjected to bilateral common carotid artery ligation (n [ 15), and sham-operated control group (n = 5). Histologic examination of the BAs and stellate ganglia was performed 2 months later. Permanent bilateral common carotid artery ligation was induced by ligation of common carotid arteries at prebifurcation levels as a model for steno-occlusive carotid artery disease. RESULTS: Mean BA volume and neuron density in stellate ganglia for all animals were 4200 mu m(3) +/- 240 and 8325 mu m(3) +/- 210. In sham- operated animals, the mean values were 4360 mu m(3) +/- 340 and 8250 mm(3) +/- 250. For the experimental group, mean volume and density in animals with slight dilatation of the BA (n = 6) were 4948 mu m(3) +/- 680 and 10,321 mm(3) +/- 120, whereas in animals with severe dilatation (n = 9), the values were 6728 mu m(3) +/- 440 and 6300 mm(3) +/- 730. An inverse association was observed between degree of BA enlargement and stellate ganglia neuronal density. CONCLUSIONS: High neuron density in stellate ganglia may protect against steno-occlusive carotid artery disease by preventing BA dilatation and aneurysm formation in the posterior circulatory arteries. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier Science Inc | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Basilar Artery | en_US |
dc.subject | Bilateral Common Carotid Artery Ligation | en_US |
dc.subject | Neuron Density in Stellate Ganglion | en_US |
dc.title | Inverse association between basilar artery volume and neuron density in the stellate ganglion following bilateral common carotid artery ligation: An experimental study | en_US |
dc.type | article | en_US |
dc.relation.ispartof | World Neurosurgery | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Beyin ve Sinir Cerrahisi Ana Bilim Dalı | en_US |
dc.identifier.volume | 100 | en_US |
dc.identifier.startpage | 138 | en_US |
dc.identifier.endpage | 143 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1016/j.wneu.2016.12.034 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.identifier.scopusquality | Q2 | en_US |