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dc.contributor.authorGüzel, Mustafa
dc.contributor.authorWatts, Joshua
dc.contributor.authorMcGilvary, Matthew
dc.contributor.authorWright, Marcus
dc.contributor.authorKiren, Sezgin
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:03:15Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:03:15Z
dc.date.issued2015en_US
dc.identifier.citationGüzel, M., Watts, J., McGilvary, M., Wright, M. ve Kiren, S. (2015). Synthesis of substituted pyridines from 1,2-nucleophilic addition products of functionalized N-acy1-2,3-dihydropyridones. Tetrahedron Letters, 56(38), 5275-5277. https://dx.doi.org/10.1016/j.tetlet.2015.07.045en_US
dc.identifier.issn0040-4039
dc.identifier.urihttps://dx.doi.org/10.1016/j.tetlet.2015.07.045
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3835
dc.descriptionWOS: 000360510700004en_US
dc.description.abstractWe describe herein a general and efficient synthetic approach toward substituted pyridines from functionalized N-acy1-2,3-dihydropyridones in two steps; 1,2-addition with organocerium reagents and subsequent oxidative aromatization with chloranil. This strategy allows the generation of pyridines with various substitution patterns and introduces a variety of substituents including aryl, alkyl, alkynyl, alkenyl, and heteroaryl groups at the desired positions.en_US
dc.description.sponsorshipWinston Salem State University NSF HBCU-UP Program [0927905]en_US
dc.description.sponsorshipWe gratefully acknowledge Winston Salem State University NSF HBCU-UP Program (0927905) for financial help. Also, we would like to thank Prof. Mark E. Welker in the department of Chemistry at Wake Forest University for their contribution and providing access to their research facilities.en_US
dc.language.isoengen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectSubstituted Pyridinesen_US
dc.subjectN-Acyl-2,3-Dihydropyridonesen_US
dc.subjectOxidative Aromatizationen_US
dc.subjectChloranilen_US
dc.subject1,2-Nucleophilic Additionen_US
dc.titleSynthesis of substituted pyridines from 1,2-nucleophilic addition products of functionalized N-acy1-2,3-dihydropyridonesen_US
dc.typearticleen_US
dc.relation.journalTetrahedron Lettersen_US
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)en_US
dc.authorid0000-0002-1423-0435en_US
dc.identifier.volume56en_US
dc.identifier.issue38en_US
dc.identifier.startpage5275en_US
dc.identifier.endpage5277en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.tetlet.2015.07.045en_US


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