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Comparison of the visual and auditory event related potentials of parkinson's disease epatients with and without cognitive impairment

Access

info:eu-repo/semantics/closedAccess

Date

2017

Author

Güner, Dilan
İsogğlu Alkaç, Ümmühan
Aktürk, Tuba
Hanoğlu, Lütfü
Güntekin, Bahar

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Citation

Güner, D., İsoğlu Alkaç, Ü., Aktürk, T., Hanoğlu, L. ve Güntekin, B. (2017). Comparison of the visual and auditory event related potentials of parkinson's disease epatients with and without cognitive impairment. 57th Annual Meeting of the Society-for-Psychophysiological-Research içinde (S94-S94. ss.). Vienna, Austria, October 11-15, 2017.

Abstract

Auditory event related potentials (ERPs) and visual evoked potentials (VEPs) were recorded from eight patients with Parkinson's disease, before and after a single dose of apomorphine. To assess the treatment effects, the patients' motor state, Benton visual retention test (BVRT), and digit span tests were also examined. After apomorphine, although motor performance improved, the ERP latencies were delayed and the N2-P3 ERP amplitude was significantly diminished by comparison with pretreatment values. These data suggest that apomorphine induces, besides its motor effects in patients with Parkinson's disease, a slowing down of cognitive processing. Preferential stimulation of dopamine autoreceptors in mesocortical and mesolimbic systems may represent a neural mechanism for these effects. Also, the posttreatment BVRT rotation errors significantly increased, suggesting an apomorphine induced impairment of visuospatial perception.

WoS Q Kategorisi

Q1

Source

57th Annual Meeting of the Society-for-Psychophysiological-Research

Volume

54

Issue

Supplement: 1

URI

https://hdl.handle.net/20.500.12511/3724

Collections

  • Bildiri Koleksiyonu [485]
  • WoS İndeksli Yayınlar Koleksiyonu [5978]



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