Ara
Toplam kayıt 8, listelenen: 1-8
Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering
(Wiley, 2020)
Regeneration of nerve tissue is a challenging issue in regenerative medicine. Especially, the peripheral nerve defects related to the accidents are one of the leading health problems. For large degeneration of peripheral ...
Functional evaluation of the tachycardia patient-derived iPSC cardiomyocytes carrying a novel pathogenic SCN5A variant
(Wiley, 2022)
Tachycardia is characterized by high beating rates that can lead to life-threatening fibrillations. Mutations in several ion-channel genes were implicated with tachycardia; however, the complex genetic contributors and ...
Defining optimal enzyme and matrix combination for replating of human induced pluripotent stem cell-derived cardiomyocytes at different levels of maturity
(Elsevier Inc., 2021)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) create an unlimited cell source for basic and translational research. Depending on the maturity of cardiac cultures and the intended applications, ...
Anatomical characterization of vagal nodose afferent innervation and ending morphologies at the murine heart using a transgenic approach
(Elsevier B.V., 2022)
Heart is an extensively innervated organ and its function is strictly coordinated by autonomic neural circuits. After pathological events such as myocardial infarction (MI), cardiac nerves undergo a structural and functional ...
Evaluation of the bilateral cardiac afferent distribution at the spinal and vagal ganglia by retrograde labeling
(Elsevier, 2021)
The identity of sensory neurons innervating the heart tissue and the extent of information reported to the brain via these neurons are poorly understood. In order to evaluate the multidimensional distribution and abundance ...
Human macrophages directly modulate iPSC-derived cardiomyocytes at healthy state and congenital arrhythmia model in vitro
(Springer Heidelberg, 2022)
The electrophysiological regulation of cardiomyocytes (CMs) by the cardiac macrophages (M Phi s) has been recently described as an unconventional role of M Phi s in the murine heart. Investigating the molecular and ...
Cardiac immunology: A new era for immune cells in the heart
(Plenum Press, 2021)
The immune system is essential for the development and homeostasis of the human body. Our current understanding of the immune system on disease pathogenesis has drastically expanded over the last decade with the definition ...
High-resolution mapping of sensory fibers at the healthy and post-myocardial infarct whole transgenic hearts
(Wiley, 2023)
The sensory nervous system is critical to maintain cardiac function. As opposed to efferent innervation, less is known about cardiac afferents. For this, we mapped the VGLUT2-expressing cardiac afferent fibers of spinal ...