dc.contributor.author | Erdoğan, Fırat | |
dc.contributor.author | Kulak, Kudret | |
dc.contributor.author | Öztürk, Özmen | |
dc.contributor.author | İpek Özahı, İlke | |
dc.contributor.author | Ceran, Ömer | |
dc.contributor.author | Seven, Hüseyin | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:02:20Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:02:20Z | |
dc.date.issued | 2016 | en_US |
dc.identifier.citation | Erdoğan, F., Kulak, K., Öztürk, Ö., İpek Özahı, İ., Ceran, Ö. ve Seven, H. (2016). Surgery vs medical treatment in the management of PFAPA syndrome: A comparative trial. Paediatrics And International Child Health, 36(4), 270-274. https://dx.doi.org/10.1179/2046905515Y.0000000051 | en_US |
dc.identifier.issn | 2046-9047 | |
dc.identifier.issn | 2046-9055 | |
dc.identifier.uri | https://dx.doi.org/10.1179/2046905515Y.0000000051 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/3621 | |
dc.description | WOS: 000390990500004 | en_US |
dc.description | PubMed ID: 26256936 | en_US |
dc.description.abstract | Background: Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is a common disorder in children but there is little or no consensus on its optimal diagnosis and management.Objectives: To compare the outcome of different management approaches - medical therapy or tonsillectomy.Methods: The medical records of children diagnosed with PFAPA between 2008 and 2013 were retrospectively reviewed according to the modified Thomas test criteria. Patients were divided into two groups: group 1 for medical treatment - corticosteroids, a single intramuscular injection of methylprednisolone, and group 2 for surgery - tonsillectomy alone or tonsillectomy plus adenoidectomy .The course of the disease including the number and duration of episodes and the presence of remission, was documented.Results: 105 patients (30 in group 1, 75 in group 2) met the study's inclusion criteria. Groups 1 and 2 were followed up for a mean (SD) of 23.6 (11.0) and 24 (10.3) months, respectively. At the end of the follow-up period, the number of episodes was 5.8 (6.3) vs 1.8 (1.9) (P<0.01) and their duration was 2.2 (1.3) vs 1.1 (0.8) days (P=0.03), both of which were significantly lower in group 2.The need for hospitalization during this period was significantly lower for group 2 at 1.1 (2.0) vs 0.1 (0.3) (P<0.01) and the remission rate in group 2 was significantly higher than in group 1 (98.6% vs 56.6%, P<0.01).Conclusion: This study demonstrated that surgery is superior to medical treatment for PFAPA in terms of increased remission rates and a decrease in the number and duration of episodes. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Medical Treatment | en_US |
dc.subject | Periodic Fever | en_US |
dc.subject | PFAPA Syndrome | en_US |
dc.subject | Surgery | en_US |
dc.title | Surgery vs medical treatment in the management of PFAPA syndrome: A comparative trial | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Paediatrics And International Child Health | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-6299-7067 | en_US |
dc.authorid | 0000-0002-8968-4079 | en_US |
dc.authorid | 0000-0003-4904-279X | en_US |
dc.identifier.volume | 36 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 270 | en_US |
dc.identifier.endpage | 274 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1179/2046905515Y.0000000051 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.identifier.scopusquality | Q2 | en_US |