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dc.contributor.authorErdoğan, Fırat
dc.contributor.authorKulak, Kudret
dc.contributor.authorÖztürk, Özmen
dc.contributor.authorİpek Özahı, İlke
dc.contributor.authorCeran, Ömer
dc.contributor.authorSeven, Hüseyin
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:20Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:20Z
dc.date.issued2016en_US
dc.identifier.citationErdoğan, F., Kulak, K., Öztürk, Ö., İpek Özahı, İ., Ceran, Ö. ve Seven, H. (2016). Surgery vs medical treatment in the management of PFAPA syndrome: A comparative trial. Paediatrics And International Child Health, 36(4), 270-274. https://dx.doi.org/10.1179/2046905515Y.0000000051en_US
dc.identifier.issn2046-9047
dc.identifier.issn2046-9055
dc.identifier.urihttps://dx.doi.org/10.1179/2046905515Y.0000000051
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3621
dc.descriptionWOS: 000390990500004en_US
dc.descriptionPubMed ID: 26256936en_US
dc.description.abstractBackground: Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is a common disorder in children but there is little or no consensus on its optimal diagnosis and management.Objectives: To compare the outcome of different management approaches - medical therapy or tonsillectomy.Methods: The medical records of children diagnosed with PFAPA between 2008 and 2013 were retrospectively reviewed according to the modified Thomas test criteria. Patients were divided into two groups: group 1 for medical treatment - corticosteroids, a single intramuscular injection of methylprednisolone, and group 2 for surgery - tonsillectomy alone or tonsillectomy plus adenoidectomy .The course of the disease including the number and duration of episodes and the presence of remission, was documented.Results: 105 patients (30 in group 1, 75 in group 2) met the study's inclusion criteria. Groups 1 and 2 were followed up for a mean (SD) of 23.6 (11.0) and 24 (10.3) months, respectively. At the end of the follow-up period, the number of episodes was 5.8 (6.3) vs 1.8 (1.9) (P<0.01) and their duration was 2.2 (1.3) vs 1.1 (0.8) days (P=0.03), both of which were significantly lower in group 2.The need for hospitalization during this period was significantly lower for group 2 at 1.1 (2.0) vs 0.1 (0.3) (P<0.01) and the remission rate in group 2 was significantly higher than in group 1 (98.6% vs 56.6%, P<0.01).Conclusion: This study demonstrated that surgery is superior to medical treatment for PFAPA in terms of increased remission rates and a decrease in the number and duration of episodes.en_US
dc.language.isoengen_US
dc.publisherTaylor & Francis Ltden_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMedical Treatmenten_US
dc.subjectPeriodic Feveren_US
dc.subjectPFAPA Syndromeen_US
dc.subjectSurgeryen_US
dc.titleSurgery vs medical treatment in the management of PFAPA syndrome: A comparative trialen_US
dc.typearticleen_US
dc.relation.ispartofPaediatrics And International Child Healthen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun Boğaz Hastalıkları Ana Bilim Dalıen_US
dc.authorid0000-0002-6299-7067en_US
dc.authorid0000-0002-8968-4079en_US
dc.authorid0000-0003-4904-279Xen_US
dc.identifier.volume36en_US
dc.identifier.issue4en_US
dc.identifier.startpage270en_US
dc.identifier.endpage274en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1179/2046905515Y.0000000051en_US
dc.identifier.wosqualityQ3en_US
dc.identifier.scopusqualityQ2en_US


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