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dc.contributor.authorNuhoğlu, Çağatay
dc.contributor.authorHepkaya, Evrim
dc.contributor.authorÖnal, Zehra Esra
dc.contributor.authorAkıcı, Narin
dc.contributor.authorGürbüz, Tamay
dc.contributor.authorAtasayan, Vildan
dc.contributor.authorCeran, Ömer
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:09Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:09Z
dc.date.issued2018en_US
dc.identifier.citationNuhoğlu, Ç., Hepkaya, E., Önal, Z. E., Akıcı, N., Gürbüz, T., Atasayan, V. ve Ceran, Ö. (2018). Immunomodulator effect of topical zinc oxide application in tuberculin skin test. Northern Clinics of Istanbul, 5(1), 37-40. https://dx.doi.org/10.14744/nci.2017.88896en_US
dc.identifier.issn2148-4902
dc.identifier.urihttps://dx.doi.org/10.14744/nci.2017.88896
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3567
dc.descriptionWOS: 000433094100008en_US
dc.descriptionPubMed ID: 29607430en_US
dc.description.abstractOBJECTIVE: We aimed to evaluate the sensitivity of tuberculin skintest (purified protein derivative-PPD) by topical zinc application on test site to improve diagnostic reliability. METHODS: We performed this study in 100 children aged 6-14 years, and plasma zinc levels were analyzed after 10-12 hours fasting. After PPD, we applied 40% zinc oxide cream on one forearm and placebo on the other forearm. PPD indurations were measured 72 hours later. RESULTS: In this study, 26% of the children showed increases in PPD induration following local zinc applications. There was no correlation between indurations size and serum zinc levels. CONCLUSION: We concluded that topical zinc cream application can enhance sensitivity of tuberculin reactivityin the diagnosis of tuberculosis.en_US
dc.language.isoengen_US
dc.publisherKare Publisheren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPurified Protein Derivativeen_US
dc.subjectTuberculin Skin Testen_US
dc.subjectZincen_US
dc.titleImmunomodulator effect of topical zinc oxide application in tuberculin skin testen_US
dc.typearticleen_US
dc.relation.ispartofNorthern Clinics of Istanbulen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.authorid0000-0002-8968-4079en_US
dc.identifier.volume5en_US
dc.identifier.issue1en_US
dc.identifier.startpage37en_US
dc.identifier.endpage40en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.14744/nci.2017.88896en_US


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