dc.contributor.author | Nuhoğlu, Çağatay | |
dc.contributor.author | Hepkaya, Evrim | |
dc.contributor.author | Önal, Zehra Esra | |
dc.contributor.author | Akıcı, Narin | |
dc.contributor.author | Gürbüz, Tamay | |
dc.contributor.author | Atasayan, Vildan | |
dc.contributor.author | Ceran, Ömer | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:02:09Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:02:09Z | |
dc.date.issued | 2018 | en_US |
dc.identifier.citation | Nuhoğlu, Ç., Hepkaya, E., Önal, Z. E., Akıcı, N., Gürbüz, T., Atasayan, V. ve Ceran, Ö. (2018). Immunomodulator effect of topical zinc oxide application in tuberculin skin test. Northern Clinics of Istanbul, 5(1), 37-40. https://dx.doi.org/10.14744/nci.2017.88896 | en_US |
dc.identifier.issn | 2148-4902 | |
dc.identifier.uri | https://dx.doi.org/10.14744/nci.2017.88896 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/3567 | |
dc.description | WOS: 000433094100008 | en_US |
dc.description | PubMed ID: 29607430 | en_US |
dc.description.abstract | OBJECTIVE: We aimed to evaluate the sensitivity of tuberculin skintest (purified protein derivative-PPD) by topical zinc application on test site to improve diagnostic reliability. METHODS: We performed this study in 100 children aged 6-14 years, and plasma zinc levels were analyzed after 10-12 hours fasting. After PPD, we applied 40% zinc oxide cream on one forearm and placebo on the other forearm. PPD indurations were measured 72 hours later. RESULTS: In this study, 26% of the children showed increases in PPD induration following local zinc applications. There was no correlation between indurations size and serum zinc levels. CONCLUSION: We concluded that topical zinc cream application can enhance sensitivity of tuberculin reactivityin the diagnosis of tuberculosis. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Kare Publisher | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Purified Protein Derivative | en_US |
dc.subject | Tuberculin Skin Test | en_US |
dc.subject | Zinc | en_US |
dc.title | Immunomodulator effect of topical zinc oxide application in tuberculin skin test | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Northern Clinics of Istanbul | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-8968-4079 | en_US |
dc.identifier.volume | 5 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 37 | en_US |
dc.identifier.endpage | 40 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.14744/nci.2017.88896 | en_US |