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dc.contributor.authorYılmaz Helvacı, Nesrin
dc.contributor.authorPolat, Burcu
dc.contributor.authorHanoğlu, Lütfü
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:59Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:59Z
dc.date.issued2016en_US
dc.identifier.citationYılmaz Helvacı, N., Polat, B. ve Hanoğlu, L. (2016). Transcranial direct current stimulation in the treatment of essential tremor: An open-label study. Neurologist, 21(2), 28-29. https://dx.doi.org/10.1097/NRL.0000000000000070en_US
dc.identifier.issn1074-7931
dc.identifier.urihttps://dx.doi.org/10.1097/NRL.0000000000000070
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3516
dc.descriptionWOS: 000375144800004en_US
dc.descriptionPubMed ID: 26926852en_US
dc.description.abstractIntroduction: Pharmacotherapy and thalamic stimulation are the most accepted methods used for the treatment of essential tremor (ET). Transcranial direct current stimulation (tDCS) is a noninvasive method for brain stimulation, especially to treat pain, cerebrovascular disease, and depression. tDCS applied to the cerebellar region has been shown to exhibit a modulating effect on the excitability of Purkinje cells and to cause primary motor cortex inhibition through the regulation of synaptic dentato-thalamo-cortical excitability. There is only 1 trial that studied the effect of tDCS on ET with 8 patients, and the results were not satisfactory. Case Series: Six ET patients were administered the Essential Tremor Rating Assessment Scale (TETRAS) and Activities of Daily Living (ADL). We applied tDCS to the dorsolateral prefrontal areas (anode) and to inion (inion at 2 mA for 20 min in 10 consecutive sessions with a 2-d break between the first and the second 5-d sessions). One month after the initial course of therapy, 5 more tDCS sessions were administered in an every-other-day manner. TETRAS and ADL scales were readministered. The Friedman test was used to assess differences in TETRAS scores and ADL over the whole time course. Conclusions: A significant improvement was observed in TETRAS and ADL scores at the end of 50 days (P = 0.015, 0.024). We concluded that although our sample group is small, tDCS might be an alternative therapy for patients with ET.en_US
dc.language.isoengen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectEssential Tremoren_US
dc.subjectNeuromodulationen_US
dc.subjectTranscranial Direct Current Stimulationen_US
dc.titleTranscranial direct current stimulation in the treatment of essential tremor: An open-label studyen_US
dc.typearticleen_US
dc.relation.ispartofNeurologisten_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalıen_US
dc.authorid0000-0003-4292-5717en_US
dc.authorid0000-0001-7566-1063en_US
dc.identifier.volume21en_US
dc.identifier.issue2en_US
dc.identifier.startpage28en_US
dc.identifier.endpage29en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1097/NRL.0000000000000070en_US
dc.identifier.wosqualityQ4en_US
dc.identifier.scopusqualityQ3en_US


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