dc.contributor.author | Acet, Mustafa | |
dc.contributor.author | Aktün, Lebriz Hale | |
dc.contributor.author | Başaranoǧlu, Serdar | |
dc.contributor.author | Yorgunlar, Betül | |
dc.contributor.author | Acet, Tuba | |
dc.contributor.author | Deregözü, Ayşegül | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:01:44Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:01:44Z | |
dc.date.issued | 2015 | en_US |
dc.identifier.citation | Acet, M., Aktün, L. H., Başaranoǧlu, S., Yorgunlar, B., Acet, T. ve Deregözü, A. (2015). Premature progesterone elevation does not affect pregnancy outcome in high-responder patients undergoing short-interval coasting in IVF cycles. Medical Science Monitor Basic Research, 21, 247-252. https://dx.doi.org/10.12659/MSMBR.896244 | en_US |
dc.identifier.issn | 2325-4416 | |
dc.identifier.issn | 2325-4394 | |
dc.identifier.uri | https://dx.doi.org/10.12659/MSMBR.896244 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/3424 | |
dc.description | WOS: 000399157000040 | en_US |
dc.description | PubMed ID: 26634938 | en_US |
dc.description.abstract | Background: We aimed to present the relationship between premature progesterone elevation (PPE) and clinical outcomes in high-responder patients who had a coasting period of < 4 days in length due to their high risk of developing ovarian hyperstimulation syndrome (OHSS) and who were treated with a long-acting gonadotropin-releasing hormone agonist (GnRH-agonist) protocol in in vitro fertilization-embryo transfer (IVF-ET) cycles. Material/Methods: This retrospective study was conducted at the University Hospital Assisted Reproductive Technology Center. The outcomes of 101 patients undergoing IVF-intracytoplasmic sperm injection (ICSI) cycles who showed a high response to COH (estradiol > 4000 pg/ml and/or > 20 follicles each >= 10 mm in diameter and at least 20% 3 15 mm) and who were coasted for < 4 days were evaluated. Number of oocytes, 2 pronuclei (PN) embryos, implantation rate, and live birth rate were measured. Results: The incidence of PPE was 32.6%. Compared with those without PPE, patients with PPE had a higher number of oocytes retrieved. Total mature and fertilized oocytes and the mean number of embryos transferred were not significantly different between groups. Live birth rates (41.9% vs. 38.7%) and implantation rates (26.5% vs. 23%) were also not significantly divergent in the PPE and non-PPE groups, respectively. Conclusions: P concentrations >= 1.3 ng/ml on the day of human chorionic gonadotropin (hCG) administration, designated in this study as PPE, does not appear to be related to adverse effects in terms of clinical outcomes in high-responder patients undergoing coasting < 4 days due to their high risk of developing OHSS treated with a long-acting GnRH-a protocol in IVF-embryo transfer cycles. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | International Scientific Literature | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Unported | * |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ | * |
dc.subject | Fertilization In Vitro | en_US |
dc.subject | Gonadotropin-Releasing Hormone | en_US |
dc.subject | Pregnancy Rate | en_US |
dc.subject | Progesterone | en_US |
dc.title | Premature progesterone elevation does not affect pregnancy outcome in high-responder patients undergoing short-interval coasting in IVF cycles | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Medical Science Monitor Basic Research | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı | en_US |
dc.identifier.volume | 21 | en_US |
dc.identifier.startpage | 247 | en_US |
dc.identifier.endpage | 252 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.12659/MSMBR.896244 | en_US |
dc.identifier.scopusquality | Q2 | en_US |