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dc.contributor.authorDemirer, Ersin
dc.contributor.authorMiller, Andrew Cate
dc.contributor.authorKunter, Erdoğan
dc.contributor.authorKartaloǧlu, Zafer
dc.contributor.authorBarnett, Scott D.
dc.contributor.authorElamin, Elamin M.
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:40Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:40Z
dc.date.issued2012en_US
dc.identifier.citationDemirer, E., Miller, A. C., Kunter, E., Kartaloǧlu, Z., Barnett, S. D. ve Elamin, E. M. (2012). Predictive models for tuberculous pleural effusions in a high tuberculosis prevalence region. Lung, 190(2), 239-248. https://dx.doi.org/10.1007/s00408-011-9342-zen_US
dc.identifier.issn0341-2040
dc.identifier.issn1432-1750
dc.identifier.urihttps://dx.doi.org/10.1007/s00408-011-9342-z
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3392
dc.descriptionWOS: 000302146900015en_US
dc.descriptionPubMed ID: 22057296en_US
dc.description.abstractPatients with pleural effusions who reside in geographic areas with a high prevalence of tuberculosis frequently have similar clinical manifestations of other diseases. The aim of our study was to develop a simple but accurate clinical score for differential diagnosis of tuberculosis pleural effusion (TPE) from non-TB pleural effusion (NTPE). This was an unblinded, prospective study of Turkish patients 18 years of age or older with pleural effusion of indeterminate etiology conducted from June 2003 to June 2005. Unconditional logistic regression models were used to discriminate TPE cases from NTPE cases. Standard errors for the area under the curve (AUC) were calculated using the Mann-Whitney method. Data were statistically significance if two-tailed P < 0.05. A total of 63.3% (157/248) of the patients had TPE while 36.7% (91/248) of the patients had other etiologies for pleural effusions. We were able to provide a predictive model of TPE that included age < 47 years and either pleural fluid adenosine deaminase enzyme (PADA) > 35 U/l or pleural serum protein ratio > 0.710. However, only the combination of age < 47 and PADA > 35 U/l was significant (odds ratio [OR]: 7.46; 95% confidence interval [CI]: 3.99-13.96). The generated summary score (range = 0-6) was significantly predictive of TPE (OR: 2.91; 95% CI: 2.18-3.89) and with high AUC (0.79). We propose an affordable model that includes age < 47 years and PADA > 35 U/l for timely diagnosis of TPE in geographical regions with a high prevalence of TB.en_US
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdenosine Deaminase Enzymeen_US
dc.subjectLactate Dehydrogenase Enzymeen_US
dc.subjectPulmonary Tuberculosisen_US
dc.subjectTuberculous Pleural Effusionen_US
dc.titlePredictive models for tuberculous pleural effusions in a high tuberculosis prevalence regionen_US
dc.typearticleen_US
dc.relation.journalLungen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalıen_US
dc.authorid0000-0003-4642-8590en_US
dc.identifier.volume190en_US
dc.identifier.issue2en_US
dc.identifier.startpage239en_US
dc.identifier.endpage248en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s00408-011-9342-zen_US


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