dc.contributor.author | Gündoğdu-Karaburun, Nalan | |
dc.contributor.author | Karaburun, Ahmet Çağrı | |
dc.contributor.author | Demirayak, Şeref | |
dc.contributor.author | Kayagil, İsmail | |
dc.contributor.author | Yurttaş, Leyla | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T20:01:39Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T20:01:39Z | |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Gündoğdu-Karaburun, N., Karaburun, A. Ç., Demirayak, Ş., Kayagil, İ. ve Yurttaş, L. (2014). Synthesis and anticancer activity of some 2-[3/4-(2-substituted phenyl-2-oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one derivatives. Letters in Drug Design & Discovery, 11(5), 578-585. https://dx.doi.org/10.2174/1570180811666140403001212 | en_US |
dc.identifier.issn | 1570-1808 | |
dc.identifier.issn | 1875-628X | |
dc.identifier.uri | https://dx.doi.org/10.2174/1570180811666140403001212 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/3383 | |
dc.description | WOS: 000335394500005 | en_US |
dc.description.abstract | The synthesis of 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1one derivatives and the investigation of their anticancer activity were studied. 2-(3- or 4-Hydroxybenzylidene)-6substituted- 2,3-dihydro-1H-inden-1-ones were reacted with suitable 2-bromoacetophenones to give 2-[3/ 4-(2-substituted phenyl-2-oxoethoxy) benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one derivatives. The structure elucidation of the synthesised compounds was performed by IR, 1H-NMR, mass spectroscopic data and elemental analyses. The anticancer screening was carried out in National Cancer Institute (NCI), USA. Notable activity was obtained for some compounds. | en_US |
dc.description.sponsorship | Anadolu University, Turkey [050301] | en_US |
dc.description.sponsorship | This work was supported by Anadolu University, Turkey (BAP Project No: 050301). NCI, USA is gratefully acknowledged for investigating anticancer activity. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Bentham Science Publishers | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | 2,3-Dihydro-1H-Inden-1-One | en_US |
dc.subject | Aurone Analogue | en_US |
dc.subject | Anticancer Activity | en_US |
dc.title | Synthesis and anticancer activity of some 2-[3/4-(2-substituted phenyl-2-oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one derivatives | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Letters in Drug Design & Discovery | en_US |
dc.department | İstanbul Medipol Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Ana Bilim Dalı | en_US |
dc.identifier.volume | 11 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 578 | en_US |
dc.identifier.endpage | 585 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.2174/1570180811666140403001212 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q3 | en_US |