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dc.contributor.authorAkış, Iraz
dc.contributor.authorEsen Gürsel, Feraye
dc.contributor.authorHacıhasanoğlu Çakmak, Neziha
dc.contributor.authorAtmaca, Gizem
dc.contributor.authorYardibi, Hasret
dc.contributor.authorAteş, Atilla
dc.contributor.authorDurak, Mehmet Hanifi
dc.contributor.authorÖztabak, Kemal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:01:31Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:01:31Z
dc.date.issued2017en_US
dc.identifier.citationAkış, I., Esen Gürsel, F., Hacıhasanoğlu Çakmak, N., Atmaca, G., Yardibi, H., Ateş, A. ... Öztabak, K. (2017). Genetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breeds. Journal of Hellenic Veterinary Medical Society, 68(3), 313-318.en_US
dc.identifier.issn1792-2720
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3323
dc.descriptionWOS: 000418954600008en_US
dc.description.abstractGrowth and meat production traits are very important in sheep breeding. Cyp19 gene has a major role in reproductive activity and growth due to its function in estrogen synthesis. Another gene affecting growth traits is Myostatin (MSTN) gene, which mainly regulates skeletal muscle growth. In this study allele frequencies of genetic polymorphism in Cyp19 and Myostatin genes were identified by PCR-RFLP method in five indigenous Turkish sheep breeds, Chiose, Imroz, Kivircik, Zom and Morkaraman. Digestion of Cyp19 gene with HaeIII only revealed uncut AA genotype and digestion of MSTN with DraI also revealed only uncut AA genotype. Both loci analyzed in this study were found to be monomorphic in five Turkish indigenous sheep breeds. These highly conserved parts of the two genes can be useful for molecular evolutionary studies in sheep. Further studies regarding association analysis of Cyp19 and MSTN in sheep should be conducted.en_US
dc.description.sponsorshipIstanbul University, Faculty of Veterinary Medicine [VET-TB-16-1, VET-TB-16-2, BEK-2016-22550, BEK-2017-24900]en_US
dc.description.sponsorshipThis study was supported by Istanbul University, Faculty of Veterinary Medicine with project numbers VET-TB-16-1, VET-TB-16-2, BEK-2016-22550 and BEK-2017-24900en_US
dc.language.isoengen_US
dc.publisherHellenic Veterinary Medical Societyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectCyp19en_US
dc.subjectMyostatinen_US
dc.subjectSheepen_US
dc.subjectSNPen_US
dc.subjectPCR-RFLPen_US
dc.titleGenetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breedsen_US
dc.typearticleen_US
dc.relation.journalJournal of Hellenic Veterinary Medical Societyen_US
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Laboratuvar Teknikleri Ana Bilim Dalıen_US
dc.authorid0000-0002-6183-5015en_US
dc.identifier.volume68en_US
dc.identifier.issue3en_US
dc.identifier.startpage313en_US
dc.identifier.endpage318en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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