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dc.contributor.authorKaraca, Oǧuz
dc.contributor.authorÇakal, Beytullah
dc.contributor.authorOmaygenç, Mehmet Onur
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorÇakal, Sinem Deniz
dc.contributor.authorKızılırmak, Filiz
dc.contributor.authorGökdeniz, Tayyar
dc.contributor.authorBarutçu, İrfan
dc.contributor.authorBoztosun, Bilal
dc.contributor.authorKılıçaslan, Fethi
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:57:32Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:57:32Z
dc.date.issued2016en_US
dc.identifier.citationKaraca, O., Çakal, B., Omaygenç, M. O., Güneş, H. M., Çakal, S. D., Kızılırmak, F. ... Kılıçaslan, F. (2016). Native electrocardiographic qrs duration after cardiac resynchronization therapy: The impact on clinical outcomes and prognosis. Journal Of Cardiac Failure, 22(10), 772-780. https://dx.doi.org/10.1016/j.cardfail.2016.04.001en_US
dc.identifier.issn1071-9164
dc.identifier.issn1532-8414
dc.identifier.urihttps://dx.doi.org/10.1016/j.cardfail.2016.04.001
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2997
dc.descriptionWOS: 000384782500006en_US
dc.descriptionPubMed ID: 27058406en_US
dc.description.abstractBackground: We investigated whether reversed electrical remodeling (RER), defined as narrowing of the native electrocardiographic QRS duration after cardiac resynchronization therapy (CRT), might predict prognosis and improvement in echocardiographic outcomes. Methods and Results: A total of 110 CRT recipients were retrospectively analyzed for the end points of death and hospitalization during 18 +/- 3 months. Native QRS durations were recorded at baseline and 6 months after CRT (when pacing was switched off to obtain an electrocardiogram) to determine RER. CRT response and mitral regurgitation (MR) improvement were defined as >= 15% reduction in left ventricular end systolic volume and absolute reduction in regurgitant volume (RegV) at 6 months, respectively. Overall, 48 patients (44%) had RER, which was associated with functional improvement (77% vs 34%; P < .001) and CRT response (81% vs 52%; P < .001) compared with those without RER. The change in the intrinsic QRS duration correlated with the reduction in RegV (r = 0.51; P < .001) and in tenting area (r = 0.34; P < .001). RER was a predictor of MR improvement (P = .023), survival (P = .043), and event-free survival (P = .028) according to multivariate analyses. Conclusions: Narrowing of the intrinsic QRS duration is associated with functional and echocardiographic CRT response, reduction in MR, and favorable prognosis after CRT.en_US
dc.language.isoengen_US
dc.publisherChurchill Livingstone Inc Medical Publishersen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNative QRS Durationen_US
dc.subjectReversed Electrical Remodelingen_US
dc.subjectCardiac Resynchronization Therapy Responseen_US
dc.subjectMitral Regurgitationen_US
dc.subjectPrognosisen_US
dc.titleNative electrocardiographic qrs duration after cardiac resynchronization therapy: The impact on clinical outcomes and prognosisen_US
dc.typearticleen_US
dc.relation.ispartofJournal Of Cardiac Failureen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.authorid0000-0002-4281-0867en_US
dc.authorid0000-0003-0230-6575en_US
dc.authorid0000-0003-2995-8792en_US
dc.authorid0000-0003-2714-4584en_US
dc.authorid0000-0003-1919-3183en_US
dc.identifier.volume22en_US
dc.identifier.issue10en_US
dc.identifier.startpage772en_US
dc.identifier.endpage780en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.cardfail.2016.04.001en_US
dc.identifier.wosqualityQ1en_US
dc.identifier.scopusqualityQ1en_US


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