dc.contributor.author | Koçak, İbrahim | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:57:00Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T19:57:00Z | |
dc.date.issued | 2017 | en_US |
dc.identifier.citation | Koçak, İ. (2017). Intravitreal aflibercept in treatment-resistant pigment epithelial detachment. International Ophthalmology, 37(3), 531-537. https://dx.doi.org/10.1007/s10792-016-0294-4 | en_US |
dc.identifier.issn | 0165-5701 | |
dc.identifier.issn | 1573-2630 | |
dc.identifier.uri | https://dx.doi.org/10.1007/s10792-016-0294-4 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/2873 | |
dc.description | WOS: 000401918500013 | en_US |
dc.description | PubMed ID: 27444307 | en_US |
dc.description.abstract | The purpose of the study was to assess the efficacy and safety of transition from ranibizumab to aflibercept intravitreal injections in treatment-resistant retinal pigment epithelial detachment (PED). The data of intravitreal ranibizumab treatment-resistant patients who have been switched to aflibercept treatment were reviewed retrospectively. After three monthly injections, bimonthly regimen was performed. The changes of PED height and radius, and the best-corrected visual acuity (BCVA) were analyzed retrospectively. Mean baseline PED height decreased from 297 +/- 151 to 122 +/- 42 mu m at month 12 (P = 0.0007). Mean baseline PED radius decreased from 2371 +/- 882 to 1859 +/- 779 mu m at month 12 (P = 0.0007). No complete PED resolution occurred in any of the patients at the end of the 12 months. Baseline BCVA improved from 0.63 +/- 0.21 to 0.43 +/- 0.17 logMar at month 12 (P = 0.0049). Mean BCVA gain was 1.4 decimal chart lines (7 letters) at month 12. Switching to aflibercept seems to have promising functional and anatomical outcomes with a reasonable complication rate in treatment-resistant PED. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Springer | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Aflibercept | en_US |
dc.subject | Pigment Epithelial Detachment | en_US |
dc.subject | Age-Related Macular Degeneration | en_US |
dc.subject | VEGF Trap | en_US |
dc.title | Intravitreal aflibercept in treatment-resistant pigment epithelial detachment | en_US |
dc.type | article | en_US |
dc.relation.ispartof | International Ophthalmology | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0003-4683-8346 | en_US |
dc.identifier.volume | 37 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 531 | en_US |
dc.identifier.endpage | 537 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1007/s10792-016-0294-4 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.identifier.scopusquality | Q2 | en_US |