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dc.contributor.authorÖnür, Seda Tural
dc.contributor.authorSökücü, Sinem Nedime
dc.contributor.authorDalar, Levent
dc.contributor.authorSeyhan, Ekrem Cengiz
dc.contributor.authorAkbaş, Ayşegül
dc.contributor.authorAltın, Sedat
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:56:25Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:56:25Z
dc.date.issued2015en_US
dc.identifier.citationÖnür, S. T., Sökücü, S. N., Dalar, L., Seyhan, E. C., Akbaş, A. ve Altın, S. (2015). Are soluble IL-2 receptor and IL-12p40 levels useful markers for diagnosis of tuberculous pleurisy? Infectious Diseases, 47(3), 150-155. https://dx.doi.org/10.3109/00365548.2014.975278en_US
dc.identifier.issn2374-4235
dc.identifier.issn2374-4243
dc.identifier.urihttps://dx.doi.org/10.3109/00365548.2014.975278
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2698
dc.descriptionWOS: 000350052900006en_US
dc.descriptionPubMed ID: 25549699en_US
dc.description.abstractBackground: The differential diagnostic utilities of the levels of soluble interleukin (IL)-12p40 and the IL-2 receptor in sera and pleural effusions were evaluated in patients with exudative pleural effusions. Methods: We enrolled a total of 120 patients with exudative pleural effusions. The clinical, radiological, and histopathological diagnoses were tuberculous pleurisy in 52, malignant pleurisy in 39, and parapneumonic effusions in 29 patients. Results: We measured serum IL-12p40 and adenosine deaminase (ADA) levels in patients with tuberculous pleurisy and in a control group treated for pleural effusion to determine if such levels were useful in the diagnosis of pleural effusion (p < 0.005). Definite microbiological or histopathological diagnoses of tuberculous pleurisy or pleural effusion were recorded, and we found that ADA and serum soluble IL-2 receptor levels aided in diagnosis (p < 0.001). The levels of ADA and soluble IL-2 in pleural effusions afforded sensitivities and specificities of 84.62% and 82.69% and of 70.59% and 80.88%, respectively. The soluble IL-2 receptor level afforded a sensitivity and specificity of 82.69% and 52.9%. IL-12p40 levels in pleural effusions and sera afforded sensitivities and specifi cities of 80.77% and 80.77% and of 60.29% and 39.71%, respectively. Conclusion: Soluble IL-2 receptor levels in patients with tuberculous pleurisy serve as markers of disease in non-endemic countries, similarly to ADA levels.en_US
dc.language.isoengen_US
dc.publisherTaylor & Francisen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTuberculosisen_US
dc.subjectPleural Effusionen_US
dc.subjectSoluble IL-2 Receptoren_US
dc.subjectIL-12p40en_US
dc.subjectAdenosine Deaminaseen_US
dc.titleAre soluble IL-2 receptor and IL-12p40 levels useful markers for diagnosis of tuberculous pleurisy?en_US
dc.typearticleen_US
dc.relation.journalInfectious Diseasesen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalıen_US
dc.identifier.volume47en_US
dc.identifier.issue3en_US
dc.identifier.startpage150en_US
dc.identifier.endpage155en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.3109/00365548.2014.975278en_US


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