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dc.contributor.authorÖzsütçü, Mustafa
dc.contributor.authorArslan, Banu
dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorGülkılık, Gökhan
dc.contributor.authorKocabora, Selim M.
dc.contributor.authorMüftüoğlu, Orkun
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:35Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:35Z
dc.date.issued2014en_US
dc.identifier.citationÖzsütçü, M., Arslan, B., Erdur, S. K., Gülkılık, G., Kocabora, S. M. ve Müftüoğlu, O. (2014). Tear osmolarity and tear film parameters in patients with unilateral pterygium. Cornea, 33(11), 1174-1178. https://dx.doi.org/10.1097/ICO.0000000000000221en_US
dc.identifier.issn0277-3740
dc.identifier.issn1536-4798
dc.identifier.urihttps://dx.doi.org/10.1097/ICO.0000000000000221
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2246
dc.descriptionWOS: 000343672300009en_US
dc.descriptionPubMed ID: 25255132en_US
dc.description.abstractPurpose: The aim of this study was to evaluate the differences in tear osmolarity and tear film parameters between pterygium-affected and healthy fellow eyes. Methods: The study enrolled 65 patients with unilateral pterygium. Tear osmolarity, tear film break-up time (TBUT), Schirmer I test measurements, fluorescein corneal staining, and conjunctival redness were evaluated. The results were compared between pterygium-affected eyes and healthy fellow eyes of the same patient (controls). The pterygium thickness was measured using optical coherence tomography. We also evaluated the relationship between pterygium thickness and tear osmolarity and between TBUT and Schirmer I test results in eyes with pterygium. Results: The mean tear osmolarity was 307 mOsm/L in pterygium-affected eyes and 294 mOsm/L in control eyes. The mean values of TBUT, Schirmer I test, corneal staining, and conjunctival redness scores were 10.3 +/- 3.4 seconds, 14.8 +/- 9.2 mm, 1.2 +/- 1.1, and 0.9 +/- 0.9 in the pterygium group, whereas the mean values were 12.3 +/- 4.4 seconds, 16.2 +/- 7.2 mm, 0.4 +/- 0.8, and 0.4 +/- 0.7 in the control group, respectively. Eyes with pterygium had significantly higher tear osmolarity levels, corneal staining, and conjunctival redness scores; and lower tear film TBUT and Schirmer I test values than eyes without pterygium (Wilcoxon signed rank test, P < 0.05). There was no significant correlation between pterygium thickness versus tear osmolarity, TBUT, and Schirmer I test values in eyes with pterygium (r = 0.159, 0.738, 0.321, respectively; P > 0.05). Conclusions: This study showed that pterygium is associated with tear hyperosmolarity and abnormal tear film function.en_US
dc.language.isoengen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectPterygiumen_US
dc.subjectTear Osmolarityen_US
dc.subjectDry Eye Diseaseen_US
dc.titleTear osmolarity and tear film parameters in patients with unilateral pterygiumen_US
dc.typearticleen_US
dc.relation.journalCorneaen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.authorid0000-0001-8954-5055en_US
dc.authorid0000-0001-9829-7268en_US
dc.authorid0000-0001-5335-3860en_US
dc.identifier.volume33en_US
dc.identifier.issue11en_US
dc.identifier.startpage1174en_US
dc.identifier.endpage1178en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1097/ICO.0000000000000221en_US


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