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dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorAydın, Rukiye
dc.contributor.authorBalevi, Ali
dc.contributor.authorÖzsütçü, Mustafa
dc.contributor.authorKocabora, Mehmet Selim
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:35Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:35Z
dc.date.issued2018en_US
dc.identifier.citationKaraman Erdur, S., Aydın, R., Balevi, A., Özsütçü, M. ve Kocabora, M. S. (2018). Dry eye assessment in patients with vitiligo. Cornea, 37(4), 412-415.en_US
dc.identifier.issn0277-3740
dc.identifier.issn1536-4798
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2245
dc.descriptionWOS: 000429590300011en_US
dc.descriptionPubMed ID: 29300260en_US
dc.description.abstractPurpose:To evaluate tear osmolarity and tear film parameters in patients with vitiligo.Methods:A total of 25 eyes of 25 patients with vitiligo with periocular involvement (group 1), 30 eyes of 30 patients with vitiligo without periocular involvement (group 2), and 20 eyes of 20 controls (group 3) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear film breakup time, scoring of ocular surface fluorescein staining using a modified Oxford scale, and tear osmolarity.Results:Mean tear osmolarity was 332 16.3 mOsm/L in group 1, 308.8 +/- 19.5 mOsm/L in group 2, and 286.3 +/- 23.4 mOsm/L in group 3 (P < 0.001). There was no significant difference in Schirmer I test results among the 3 groups (16.5 +/- 3.2 mm in group 1, 16.3 +/- 4.7 mm in group 2, and 17.4 +/- 4.2 mm in group 3) (P = 0.175). Tear film breakup time measurements in groups 1 (9.8 +/- 3.5 seconds) and 2 (10.1 +/- 4.3 seconds) were significantly lower than those in group 3 (18.5 +/- 4.0 seconds) (P <0.001). There was no significant difference among the 3 groups on the Oxford scale (0.04 +/- 0.70 in group 1, 0.03 +/- 0.33 in group 2, and 0.03 +/- 0.20 in group 3) (P = 0.865). The mean Ocular Surface Disease Index score was significantly higher in groups 1 and 2 than in group 3 (42.1 +/- 16.5 in group 1, 39.9 +/- 17.3 in group 2, and 12.3 +/- 11.6 in group 3) (P <0.001). Conclusions:This study showed that vitiligo is associated with tear hyperosmolarity and tear film dysfunction. Patients with vitiligo with periocular involvement may be more prone to dry eye than those without ocular involvement.en_US
dc.language.isoengen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectDry Eyeen_US
dc.subjectOcular Surfaceen_US
dc.subjectMeibomian Gland Dysfunctionen_US
dc.subjectTear Osmolarityen_US
dc.subjectVitiligoen_US
dc.subjectPeriocularen_US
dc.titleDry eye assessment in patients with vitiligoen_US
dc.typearticleen_US
dc.relation.journalCorneaen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalıen_US
dc.authorid0000-0001-9829-7268en_US
dc.authorid0000-0003-0668-3749en_US
dc.authorid0000-0001-5057-0405en_US
dc.authorid0000-0001-8954-5055en_US
dc.authorid0000-0001-5335-3860en_US
dc.identifier.volume37en_US
dc.identifier.issue4en_US
dc.identifier.startpage412en_US
dc.identifier.endpage415en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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