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dc.contributor.authorEmek-Savaş, Derya Durusu
dc.contributor.authorÖzmüş, Gülin
dc.contributor.authorGüntekin, Bahar
dc.contributor.authorDönmez Çolakoğlu, Berril
dc.contributor.authorÇakmur, Raif
dc.contributor.authorBaşar, Erol
dc.contributor.authorYener, Görsev G.
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:16Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:16Z
dc.date.issued2017en_US
dc.identifier.citationEmek-Savaş, D. D., Özmüş, G., Güntekin, B., Dönmez Çolakoğlu, B., Çakmur, R., Başar, E. ve Yener, G. G. (2017). Decrease of delta oscillatory responses in cognitively normal parkinson's disease. Clinical Eeg and Neuroscience, 48(5), 355-364. https://dx.doi.org/10.1177/1550059416666718en_US
dc.identifier.issn1550-0594
dc.identifier.issn2169-5202
dc.identifier.urihttps://dx.doi.org/10.1177/1550059416666718
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2184
dc.descriptionWOS: 000407132800007en_US
dc.descriptionPubMed ID: 27582502en_US
dc.description.abstractParkinson's disease (PD) is a common progressive neurodegenerative disorder. This study aims to compare sensory-evoked oscillations (SEOs) and event-related oscillations (EROs) of visual modality in cognitively normal PD patients and healthy controls. Sixteen PD and 16 age-, gender-, and education-matched healthy controls participated in the study. A simple flashlight was used for SEO and a classical visual oddball paradigm was used for target ERO. Oscillatory responses in the delta frequency range (0.5-3.5 Hz) were examined. Significantly lower delta ERO and SEO responses were found in PD patients than healthy controls. Delta ERO responses were decreased at all frontal, central and parietal locations, whereas delta SEO responses were decreased over mid and right central locations in PD. According to the notion that SEO reflects the activity of sensory networks and ERO reflects cognitive networks, these findings indicate that PD patients have impairments in both cognitive and sensory networks of visual modality. Decreased delta ERO responses indicate that the subliminal cognitive changes in PD can be detected by electrophysiological methods. These results demonstrate that brain oscillatory responses have the potential to be studied as a biomarker for visual cognitive and sensory networks in PD.en_US
dc.language.isoengen_US
dc.publisherSage Publications Incen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectParkinson's Diseaseen_US
dc.subjectEvent-Related Oscillationsen_US
dc.subjectSensory-Evoked Oscillationsen_US
dc.subjectP300en_US
dc.titleDecrease of delta oscillatory responses in cognitively normal parkinson's diseaseen_US
dc.typearticleen_US
dc.relation.ispartofClinical Eeg and Neuroscienceen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalıen_US
dc.authorid0000-0002-0860-0524en_US
dc.identifier.volume48en_US
dc.identifier.issue5en_US
dc.identifier.startpage355en_US
dc.identifier.endpage364en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1177/1550059416666718en_US
dc.identifier.wosqualityQ4en_US
dc.identifier.scopusqualityQ2en_US


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