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dc.contributor.authorAydın, Rukiye
dc.contributor.authorÖzsütçü, Mustafa
dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorDikkaya, Funda
dc.contributor.authorBalevi, Ali
dc.contributor.authorÖzbek, Merve
dc.contributor.authorŞentürk, Fevzi
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:55Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:55Z
dc.date.issued2018en_US
dc.identifier.citationAydın, R., Özsütçü, M., Karaman Erdur, S., Dikkaya, F., Balevi, A., Özbek, M. ve Şentürk, F. (2018). The assessment of macular electrophysiology and macular morphology in patients with vitiligo. International Ophthalmology, 38(1), 233-239. https://dx.doi.org/10.1007/s10792-017-0452-3en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.urihttps://dx.doi.org/10.1007/s10792-017-0452-3
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2104
dc.descriptionWOS: 000428760800034en_US
dc.descriptionPubMed ID: 28108905en_US
dc.description.abstractPurpose We aimed to analyze the electrophysiologic function and morphology of macula in vitiligo patients. Methods Seventeen patients with vitiligo and 11 healthy subjects were studied. All participants underwent multifocal electroretinography (mfERG) and spectral domain optical coherence tomography (SD-OCT) evaluations. The mfERG (P1 mfERG responses central and peripheral) and retinal layer segmentation parameters (nine ETDRS subfields) were compared in vitiligo and control groups. Results The mean P1 response amplitudes were significantly decreased in central and peripheral rings of the fovea in patients with vitiligo compared with controls (p = 0.002 and p = 0.006, respectively). There was a tendency toward a prolonged mean implicit time for both central and peripheral in patients with vitiligo compared to controls, however, with no statistical significance (p = 0.453 and p = 0.05, respectively). There was no statistically significant difference in all retinal layers thickness between two groups. Conclusion In patients with vitiligo, while photoreceptor segment preserved in SD-OCT, mfERG reduced showing potential decline in central retinal function. This study showed a potential decline in central retinal function in patients with vitiligo even if they have normal fundus appearance and SD-OCT findings.en_US
dc.language.isoengen_US
dc.publisherSpringer Netherlandsen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectVitiligoen_US
dc.subjectMultifocal Electroretinographyen_US
dc.subjectPhotoreceptor Functionen_US
dc.subjectSpectral Domain Optical Coherence Tomographyen_US
dc.titleThe assessment of macular electrophysiology and macular morphology in patients with vitiligoen_US
dc.typearticleen_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalıen_US
dc.authorid0000-0003-0668-3749en_US
dc.authorid0000-0001-8954-5055en_US
dc.authorid0000-0001-9829-7268en_US
dc.authorid0000-0003-2312-2521en_US
dc.authorid0000-0001-5057-0405en_US
dc.authorid0000-0002-4280-5718en_US
dc.authorid0000-0002-8851-6559en_US
dc.identifier.volume38en_US
dc.identifier.issue1en_US
dc.identifier.startpage233en_US
dc.identifier.endpage239en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s10792-017-0452-3en_US
dc.identifier.wosqualityQ3en_US
dc.identifier.scopusqualityQ2en_US


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