A novel biochemical marker for predicting the severity of ACS with unstable angina pectoris: Asprosin
MetadataShow full item record
CitationAcara, A., Bolatkale, M., Kızıloğlu, İ., İbişoğlu, E. ve Can, Ç. (2018). A novel biochemical marker for predicting the severity of ACS with unstable angina pectoris: Asprosin. American Journal of Emergency Medicine, 36(8), 1504-1505. https://dx.doi.org/10.1016/j.ajem.2017.12.032
Ischemic Heart Disease (IHD) is the leading cause of death world-wide, accounting for 12.7% of global mortality . Acute Coronary Syn-drome (ACS) covers a wide spectrum of clinical conditions ranging fromunstable angina to Non-ST Elevation Myocardial Infarction (N-STEMI)and ST Elevation Myocardial Infarction (STEMI). New treatments andmanagement guidelines emerge for the care of patients with ACS; riskstratification is the cornerstone in the initial evaluation of these patients . That inflammatory mediators play a role duringthe evolution of ACSis indicated by the widespread coronary inflammation found during un-stable angina pectoris (UAP), throughout theentire coronary artery bed,and in the extent that ACS outcome is related to a concurrent inflamma-toryresponse[3,4] . Circulatingasprosin,a protein hormone, responds tolow dietary glucose by triggering the release of liver glucose stores, andthe reduction of asprosin protects against the hyperinsulinism associat-ed with metabolic syndrome.