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dc.contributor.authorÜnal, Semra
dc.contributor.authorEkren, Nazmi
dc.contributor.authorŞengil, Ahmet Zeki
dc.contributor.authorOktar, Faik Nüzhet
dc.contributor.authorIrmak, Ster
dc.contributor.authorOral, Özlem
dc.contributor.authorŞahin, Yeşim Müge
dc.contributor.authorKılıç, Osman Fatih
dc.contributor.authorAgathopoulos, Simeon
dc.contributor.authorGündüz, Oğuzhan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:50:20Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:50:20Z
dc.date.issued2018en_US
dc.identifier.citationÜnal, S., Ekren, N., Şengil, A., Oktar, F., Irmak, S., Oral, Ö. ... Gündüz, O. (2018). Synthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitride. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106(6), 2384-2392. https://dx.doi.org/10.1002/jbm.b.34046en_US
dc.identifier.issn1552-4973
dc.identifier.issn1552-4981
dc.identifier.urihttps://dx.doi.org/10.1002/jbm.b.34046
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1956
dc.descriptionWOS: 000442988800030en_US
dc.descriptionPubMed ID: 29168913en_US
dc.description.abstractHydroxyapatite (HA), obtained from bovine bones, was successfully reinforced with hexagonal boron nitrite (h-BN).h-BN/HA composites, with BN content up to 1.5 wt %, were sintered at various temperatures between 1000 and 1300 degrees C, in air. Well-sintered samples were obtained after sintering at 1200 and 1300 degrees C. The presence of h-BN contributed to dense, fine, and well-crystallized microstructure. The results of X-ray diffraction analysis and FT-IR spectroscopy showed that the produced composites comprised biphasic beta-TCP/HCA (HCA: carbonate partially substituted HA). High values of mechanical properties were achieved, namely compression strength 155 MPa for the sample 0.5% h-BN/HA and Vickers microhardness of 716 HV for the samples 1.5% h-BN/HA, both sintered at 1300 degrees C. U2OS human bone osteosarcoma proliferation and cell viability showed no adverse effect in the presence of h-BN/HA, suggesting the potential use of the produced materials as safe biomaterials in bone tissue engineering.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectCompositesen_US
dc.subjectHydroxyapatiteen_US
dc.subjectBovine Boneen_US
dc.subjectHexagonal Boron Nitrideen_US
dc.subjectBioceramicen_US
dc.titleSynthesis, characterization, and biological properties of composites of hydroxyapatite and hexagonal boron nitrideen_US
dc.typearticleen_US
dc.relation.ispartofJournal of Biomedical Materials Research Part B-Applied Biomaterialsen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalıen_US
dc.identifier.volume106en_US
dc.identifier.issue6en_US
dc.identifier.startpage2384en_US
dc.identifier.endpage2392en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1002/jbm.b.34046en_US
dc.identifier.wosqualityQ2en_US
dc.identifier.scopusqualityQ2en_US


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