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dc.contributor.authorZeng, Guohua
dc.contributor.authorZhang, Tao
dc.contributor.authorAgrawal, Madhu
dc.contributor.authorHe, Xiang
dc.contributor.authorZhang, Wei
dc.contributor.authorXiao, Kefeng
dc.contributor.authorLi, Hulin
dc.contributor.authorLi, Xuedong
dc.contributor.authorXu, Changbao
dc.contributor.authorYang, Sixing
dc.contributor.authorde la Rosette, Jean J. M. C. H.
dc.contributor.authorFan, Junhong
dc.contributor.authorZhu, Wei
dc.contributor.authorSarıca, Kemal
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:49:58Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:49:58Z
dc.date.issued2018en_US
dc.identifier.citationZeng, G., Zhang, T., Agrawal, M., He, X., Zhang, W., Xiao, K. ... Sarıca, K. (2018). Super-mini percutaneous nephrolithotomy (SMP) vs retrograde intrarenal surgery for the treatment of 1-2 cm lower-pole renal calculi: An international multicentre randomised controlled trial. BJU International, 122(6), 1034-1040. https://dx.doi.org/10.1111/bju.14427en_US
dc.identifier.issn1464-4096
dc.identifier.issn1464-410X
dc.identifier.urihttps://dx.doi.org/10.1111/bju.14427
dc.identifier.urihttps://hdl.handle.net/20.500.12511/1832
dc.descriptionWOS: 000454359900022en_US
dc.descriptionPubMed ID: 29873874en_US
dc.description.abstractObjectives To compare the safety and effectiveness of super-minipercutaneous nephrolithotomy (SMP) and retrograde intrarenal surgery (RIRS) for the treatment of 1-2 cm lowerpole renal calculi (LPC). Patients and Methods An international multicentre, prospective, randomised, unblinded controlled study was conducted at 10 academic medical centres in China, India, and Turkey, between August 2015 and June 2017. In all, 160 consecutive patients with 1-2 cm LPC were randomised to receive SMP or RIRS. The primary endpoint was stone-free rate (SFR). Stone-free status was defined as no residual fragments of >= 0.3 cm on plain abdominal radiograph of the kidneys, ureters and bladder, and ultrasonography at 1-day and on computed tomography at 3-months after operation. Secondary endpoints included blood loss, operating time, postoperative pain scores, auxiliary procedures, complications, and hospital stay. Postoperative follow-up was scheduled at 3 months. Analysis was by intention-totreat. The trial was registered at http://clinicaltrials. gov/ (NCT02519634). Results The two groups had similar baseline characteristics. The mean (SD) stone diameters were comparable between the groups, at 1.50 (0.29) cm for the SMP group vs 1.43 (0.34) cm for the RIRS group (P = 0.214). SMP achieved a significantly better 1-day and 3-month SFR than RIRS (1-day SFR 91.2% vs 71.2%, P = 0.001; 3-months SFR 93.8% vs 82.5%, P = 0.028). The auxiliary procedure rate was lower in the SMP group. RIRS was found to be superior with lower haemoglobin drop and less postoperative pain. Blood transfusion was not required in either group. There was no significant difference in operating time, hospital stay, and complication rates, between the groups. Conclusions SMP was more effective than RIRS for treating 1-2 cm LPC in terms of a better SFR and lesser auxiliary procedure rate. The complications and hospital stay were comparable. RIRS has the advantage of less postoperative pain.en_US
dc.description.sponsorshipNational Natural Science Foundation of China [81670643, 81601273, 81370804]; Science and Technology Planning Project of Guangdong Province [2017B030314108]; Guangzhou Science Technology and Innovation Commission [201604020001, 201704020193]en_US
dc.description.sponsorshipThis study was supported in part by National Natural Science Foundation of China (No. 81670643, No. 81601273 and No. 81370804). Additional funding was provided by Science and Technology Planning Project of Guangdong Province (No. 2017B030314108) and Guangzhou Science Technology and Innovation Commission (No. 201604020001 and No. 201704020193).en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSuper-Mini Percutaneous Nephrolithotomyen_US
dc.subjectRetrograde Intrarenal Surgeryen_US
dc.subjectLower-Pole Renal Calculien_US
dc.titleSuper-mini percutaneous nephrolithotomy (SMP) vs retrograde intrarenal surgery for the treatment of 1-2 cm lower-pole renal calculi: An international multicentre randomised controlled trialen_US
dc.typearticleen_US
dc.relation.journalBJU Internationalen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalıen_US
dc.authorid0000-0002-6308-1763en_US
dc.identifier.volume122en_US
dc.identifier.issue6en_US
dc.identifier.startpage1034en_US
dc.identifier.endpage1040en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1111/bju.14427en_US


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