dc.contributor.author | Gençoğlu, Türkan | |
dc.contributor.author | Duman, Fatma Demir | |
dc.contributor.author | Olcay, Keziban | |
dc.contributor.author | Acar, Havva Yağcı | |
dc.contributor.author | Avcı, Duygu | |
dc.date.accessioned | 10.07.201910:49:13 | |
dc.date.accessioned | 2019-07-10T19:49:56Z | |
dc.date.available | 10.07.201910:49:13 | |
dc.date.available | 2019-07-10T19:49:56Z | |
dc.date.issued | 2018 | en_US |
dc.identifier.citation | Gençoğlu, T., Duman, F., Olcay, K., Acar, H. ve Avcı, D. (2018). Synthesis and photopolymerizations of first monomers with phosphonate and bisphosphonate or phosphonic and bisphosphonic acid functionalities for potential dental applications. Journal of Polymer Science Part a Polymer Chemistry, 56(24), 2739-2751. https://dx.doi.org/10.1002/pola.29260 | en_US |
dc.identifier.issn | 0887-624X | |
dc.identifier.issn | 1099-0518 | |
dc.identifier.uri | https://dx.doi.org/10.1002/pola.29260 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/1822 | |
dc.description | WOS: 000450460600005 | en_US |
dc.description.abstract | The first monomers containing both phosphonate and bisphosphonate (M1) or phosphonic and bisphosphonic acid (M2) functionalities are synthesized, aiming to improve binding abilities of self-etching adhesive systems and composites: An amine having both phosphonate and bisphosphonate functionalities is prepared via Michael addition reaction between diethyl (6-aminohexyl)phosphonate and tetraethyl vinylidene bisphosphonate, its reaction with 2-isocyanatoethyl methacrylate gives M1 which is converted to M2 by selective dealkylation of the phosphonate/bisphosphonate ester groups. Their copolymerization with commercial dental monomers (bisphenol A glycidyl methacrylate, triethylene glycol dimethacrylate, and 2-hydroxyethyl methacrylate) investigated by photo-differential scanning calorimetry shows adequate photopolymerization rate and conversion. X-ray diffraction, Fourier transform infrared, and X-ray photoelectron spectroscopy analyses of M2-treated hydroxyapatite particles show formation of stable M2-calcium salts. These monomers are assessed to be not toxic according to MTT standards by in vitro cytotoxicity studies with NIH 3T3, U2OS, and Saos-2 cells. All these properties make these monomers potential candidates as biocompatible components for dental adhesives and composites. | en_US |
dc.description.sponsorship | Scientific and Technological Research Council of Turkey (TUBITAK) [215Z060]; Bogazici University Research Fund [11680] | en_US |
dc.description.sponsorship | This research has been financially supported by The Scientific and Technological Research Council of Turkey (TUBITAK; 215Z060) and Bogazici University Research Fund (11680). The authors would like to thank Ozlem Karahan for XRD measurements. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Bisphosphonic Acid | en_US |
dc.subject | Dental Adhesive | en_US |
dc.subject | Hydroxyapatite | en_US |
dc.subject | Photopolymerization | en_US |
dc.subject | Phosphonate | en_US |
dc.title | Synthesis and photopolymerizations of first monomers with phosphonate and bisphosphonate or phosphonic and bisphosphonic acid functionalities for potential dental applications | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Journal of Polymer Science Part a Polymer Chemistry | en_US |
dc.department | İstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Endodonti Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-2168-710X | en_US |
dc.identifier.volume | 56 | en_US |
dc.identifier.issue | 24 | en_US |
dc.identifier.startpage | 2739 | en_US |
dc.identifier.endpage | 2751 | en_US |
dc.relation.ec | info:eu-repo/grantAgreement/TUBITAK/SOBAG/215Z060 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1002/pola.29260 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.scopusquality | Q1 | en_US |